Tenascin-C at a glance

KS Midwood, M Chiquet, RP Tucker… - Journal of cell …, 2016 - journals.biologists.com
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several
molecular forms that are created through alternative splicing and protein modifications. It is …

Clinical risk factors for Achilles tendinopathy: a systematic review

AC Van der Vlist, SJ Breda, EHG Oei… - British journal of sports …, 2019 - bjsm.bmj.com
Background Achilles tendinopathy is a common problem, but its exact aetiology remains
unclear. Objective To evaluate the association between potential clinical risk factors and …

Achilles pain, stiffness, and muscle power deficits: midportion Achilles tendinopathy revision 2018: clinical practice guidelines linked to the International Classification …

RL Martin, R Chimenti, T Cuddeford, J Houck… - Journal of Orthopaedic & …, 2018 - jospt.org
The Orthopaedic Section of the American Physical Therapy Association (APTA) has an
ongoing effort to create evidence-based practice guidelines for orthopaedic physical therapy …

Advances in sports genomics

II Ahmetov, ECR Hall, EA Semenova… - Advances in Clinical …, 2022 - Elsevier
Sports genomics is the scientific discipline that focuses on the organization and function of
the genome in elite athletes, and aims to develop molecular methods for talent identification …

Internal affairs: tenascin-C as a clinically relevant, endogenous driver of innate immunity

AM Marzeda, KS Midwood - Journal of Histochemistry & …, 2018 - journals.sagepub.com
To protect against danger, the innate immune system must promptly and accurately sense
alarm signals, and mount an appropriate response to restore homeostasis. One …

[HTML][HTML] Tendon and ligament genetics: how do they contribute to disease and injury? A narrative review

WJ Ribbans, AV September, M Collins - Life, 2022 - mdpi.com
A significant proportion of patients requiring musculoskeletal management present with
tendon and ligament pathology. Our understanding of the intrinsic and extrinsic mechanisms …

Genetic Variants and Hamstring Injury in Soccer: An Association and Validation Study.

JON Larruskain, D Celorrio, I Barrio… - Medicine and science …, 2018 - europepmc.org
Purpose This study aimed to investigate the association of candidate single nucleotide
polymorphisms (SNP) with noncontact hamstring muscle injuries in elite soccer players and …

Genome-wide association screens for Achilles tendon and ACL tears and tendinopathy

SK Kim, TR Roos, AK Roos, JP Kleimeyer, MA Ahmed… - PloS one, 2017 - journals.plos.org
Achilles tendinopathy or rupture and anterior cruciate ligament (ACL) rupture are substantial
injuries affecting athletes, associated with delayed recovery or inability to return to …

Defects in tendon, ligament, and enthesis in response to genetic alterations in key proteoglycans and glycoproteins: a review

SC Juneja, C Veillette - Arthritis, 2013 - Wiley Online Library
This review summarizes the genetic alterations and knockdown approaches published in
the literature to assess the role of key proteoglycans and glycoproteins in the structural …

Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

W Meng, MJ Adams, CNA Palmer, J Shi… - Communications …, 2019 - nature.com
Knee pain is one of the most common musculoskeletal complaints that brings people to
medical attention. Approximately 50% of individuals over the age of 50 report an experience …