Clinical findings, underlying pathogenetic processes and treatment of vascular dysfunction in autosomal dominant polycystic kidney disease

J Zhu, F Liu, J Mao - Renal Failure, 2023 - Taylor & Francis
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder
characterized by the development of fluid-filled cysts in the kidneys. The primary cause of …

Management of hypertension and associated cardiovascular disease in autosomal dominant polycystic kidney disease

FF Rahbari-Oskoui - Advances in Kidney Disease and Health, 2023 - Elsevier
Autosomal dominant polycystic kidney disease is the most commonly inherited disease of
the kidneys affecting an estimated 12,000,000 people in the world. Autosomal dominant …

Characteristics of patients with autosomal polycystic kidney disease reaching kidney failure by age 40

S Wigerinck, P Schellekens, BH Smith, C Hanna… - Pediatric …, 2025 - Springer
Background Autosomal dominant polycystic kidney disease (ADPKD) demonstrates broad
genetic and phenotypic variability, with kidney failure (KF) occurring across a wide age …

Empagliflozin in patients with autosomal dominant polycystic kidney disease (EMPA-PKD): study protocol for a randomised controlled trial

E Bahlmann-Kroll, S Häckl, S Kramer, VC Wulfmeyer… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary
condition that causes the formation of cysts primarily in the kidneys. The continuous growth …

Microvascular perfusion, perfused boundary region and glycocalyx shedding in patients with autosomal dominant polycystic kidney disease: results from the …

A Fuchs, J Dederichs, S Arjune, P Todorova… - Clinical kidney …, 2023 - academic.oup.com
Background Vascular abnormalities and endothelial dysfunction are part of the spectrum of
autosomal dominant polycystic kidney disease (ADPKD). The mechanisms behind these …

Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response

T Hendrickson, A Giese, M Fiedler, W Perez… - bioRxiv, 2024 - biorxiv.org
Background The increasing prevalence of atrial fibrillation (AF) and chronic kidney diseases
highlights the need for a deeper comprehension of the molecular mechanisms linking them …