Mechanism of antibacterial resistance, strategies and next-generation antimicrobials to contain antimicrobial resistance: A review

WY Belay, M Getachew, BA Tegegne… - Frontiers in …, 2024 - frontiersin.org
Antibacterial drug resistance poses a significant challenge to modern healthcare systems,
threatening our ability to effectively treat bacterial infections. This review aims to provide a …

Virulence Potential and Treatment Options of Multidrug-Resistant (MDR) Acinetobacter baumannii

S Kumar, R Anwer, A Azzi - Microorganisms, 2021 - mdpi.com
Acinetobacter baumannii is an opportunistic pathogen which is undoubtedly known for a
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …

Characterization of genes related to the efflux pump and porin in multidrug-resistant Escherichia coli strains isolated from patients with COVID-19 after secondary …

AR Ganjo, STJ Balaky, AH Mawlood, SB Smail… - BMC microbiology, 2024 - Springer
Background Escherichia coli (E. coli) is a multidrug resistant opportunistic pathogen that can
cause secondary bacterial infections in patients with COVID-19. This study aimed to …

[HTML][HTML] Antimicrobial resistance: is there a 'light'at the end of the tunnel?

LG Leanse, S Marasini, C Dos Anjos, T Dai - Antibiotics, 2023 - mdpi.com
In recent years, with the increases in microorganisms that express a multitude of
antimicrobial resistance (AMR) mechanisms, the threat of antimicrobial resistance in the …

[HTML][HTML] Clinical status of efflux resistance mechanisms in gram-negative bacteria

A Davin-Regli, JM Pages, A Ferrand - Antibiotics, 2021 - mdpi.com
Antibiotic efflux is a mechanism that is well-documented in the phenotype of multidrug
resistance in bacteria. Efflux is considered as an early facilitating mechanism in the bacterial …

[HTML][HTML] Activity and resistance mechanisms of the third generation tetracyclines tigecycline, eravacycline and omadacycline against nationwide Spanish collections of …

P García, P Guijarro-Sánchez… - Biomedicine & …, 2024 - Elsevier
Introduction The rise in multidrug-resistant bacteria challenges clinical microbiology.
Tigecycline, eravacycline, and omadacycline show promise against carbapenem-resistant …

[HTML][HTML] Multi-drug resistant Acinetobacter baumannii: phenotypic and genotypic resistance profiles and the associated risk factors in teaching hospital in Jordan

MH Gharaibeh, YM Abandeh, ZA Elnasser… - Journal of Infection and …, 2024 - Elsevier
Background This study aimed to determine the prevalence of Antimicrobial Resistance
Genes (ARGs), with a focus on colistin resistance in clinical A. baumannii, as well as the risk …

[HTML][HTML] Genomic insights into resistome, virulome, and mobilome as organic contaminants of ESKAPE pathogens and E. coli recovered from milk, farm workers, and …

R Hao, M Shoaib, M Tang, Z Cao, G Liu, Y Zhang… - Emerging …, 2024 - Elsevier
The ESKAPE pathogens and E. coli are of significant public health concern and are listed
among the top priorities of the World Health Organization. These pathogens are equally …

Dairy farm waste: A potential reservoir of diverse antibiotic resistance and virulence genes in aminoglycoside-and beta-lactam-resistant Escherichia coli in Gansu …

M Shoaib, M Tang, AI Aqib, X Zhang, Z Wu, Y Wen… - Environmental …, 2024 - Elsevier
Aminoglycosides (AGs) and beta-lactams are the most commonly used antimicrobials in
animal settings, particularly on dairy farms. Dairy farm waste is an important reservoir of …

Identification of a novel plasmid-mediated tigecycline resistance-related gene, tet(Y), in Acinetobacter baumannii

Z Wang, H Li, J Zhang, X Wang… - Journal of …, 2022 - academic.oup.com
Objectives To characterize a novel plasmid-mediated tigecycline resistance-related gene, tet
(Y), in a clinical Acinetobacter baumannii isolate from China. Methods The tet (Y)-encoded …