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Mechanism of antibacterial resistance, strategies and next-generation antimicrobials to contain antimicrobial resistance: A review
Antibacterial drug resistance poses a significant challenge to modern healthcare systems,
threatening our ability to effectively treat bacterial infections. This review aims to provide a …
threatening our ability to effectively treat bacterial infections. This review aims to provide a …
Virulence Potential and Treatment Options of Multidrug-Resistant (MDR) Acinetobacter baumannii
Acinetobacter baumannii is an opportunistic pathogen which is undoubtedly known for a
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …
Characterization of genes related to the efflux pump and porin in multidrug-resistant Escherichia coli strains isolated from patients with COVID-19 after secondary …
Background Escherichia coli (E. coli) is a multidrug resistant opportunistic pathogen that can
cause secondary bacterial infections in patients with COVID-19. This study aimed to …
cause secondary bacterial infections in patients with COVID-19. This study aimed to …
[HTML][HTML] Antimicrobial resistance: is there a 'light'at the end of the tunnel?
In recent years, with the increases in microorganisms that express a multitude of
antimicrobial resistance (AMR) mechanisms, the threat of antimicrobial resistance in the …
antimicrobial resistance (AMR) mechanisms, the threat of antimicrobial resistance in the …
[HTML][HTML] Clinical status of efflux resistance mechanisms in gram-negative bacteria
A Davin-Regli, JM Pages, A Ferrand - Antibiotics, 2021 - mdpi.com
Antibiotic efflux is a mechanism that is well-documented in the phenotype of multidrug
resistance in bacteria. Efflux is considered as an early facilitating mechanism in the bacterial …
resistance in bacteria. Efflux is considered as an early facilitating mechanism in the bacterial …
[HTML][HTML] Activity and resistance mechanisms of the third generation tetracyclines tigecycline, eravacycline and omadacycline against nationwide Spanish collections of …
P García, P Guijarro-Sánchez… - Biomedicine & …, 2024 - Elsevier
Introduction The rise in multidrug-resistant bacteria challenges clinical microbiology.
Tigecycline, eravacycline, and omadacycline show promise against carbapenem-resistant …
Tigecycline, eravacycline, and omadacycline show promise against carbapenem-resistant …
[HTML][HTML] Multi-drug resistant Acinetobacter baumannii: phenotypic and genotypic resistance profiles and the associated risk factors in teaching hospital in Jordan
Background This study aimed to determine the prevalence of Antimicrobial Resistance
Genes (ARGs), with a focus on colistin resistance in clinical A. baumannii, as well as the risk …
Genes (ARGs), with a focus on colistin resistance in clinical A. baumannii, as well as the risk …
[HTML][HTML] Genomic insights into resistome, virulome, and mobilome as organic contaminants of ESKAPE pathogens and E. coli recovered from milk, farm workers, and …
R Hao, M Shoaib, M Tang, Z Cao, G Liu, Y Zhang… - Emerging …, 2024 - Elsevier
The ESKAPE pathogens and E. coli are of significant public health concern and are listed
among the top priorities of the World Health Organization. These pathogens are equally …
among the top priorities of the World Health Organization. These pathogens are equally …
Dairy farm waste: A potential reservoir of diverse antibiotic resistance and virulence genes in aminoglycoside-and beta-lactam-resistant Escherichia coli in Gansu …
M Shoaib, M Tang, AI Aqib, X Zhang, Z Wu, Y Wen… - Environmental …, 2024 - Elsevier
Aminoglycosides (AGs) and beta-lactams are the most commonly used antimicrobials in
animal settings, particularly on dairy farms. Dairy farm waste is an important reservoir of …
animal settings, particularly on dairy farms. Dairy farm waste is an important reservoir of …
Identification of a novel plasmid-mediated tigecycline resistance-related gene, tet(Y), in Acinetobacter baumannii
Z Wang, H Li, J Zhang, X Wang… - Journal of …, 2022 - academic.oup.com
Objectives To characterize a novel plasmid-mediated tigecycline resistance-related gene, tet
(Y), in a clinical Acinetobacter baumannii isolate from China. Methods The tet (Y)-encoded …
(Y), in a clinical Acinetobacter baumannii isolate from China. Methods The tet (Y)-encoded …