Maternal immune activation: Implications for neuropsychiatric disorders

ML Estes, AK McAllister - Science, 2016 - science.org
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum
disorder and schizophrenia. Animal models corroborate this link and demonstrate that …

Neuroinflammation as a risk factor for attention deficit hyperactivity disorder

GA Dunn, JT Nigg, EL Sullivan - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Abstract Attention Deficit Hyperactivity Disorder (ADHD) is a persistent, and impairing
pediatric-onset neurodevelopmental condition. Its high prevalence, and recurrent …

[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The develo** brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

Schizophrenia and influenza at the centenary of the 1918-1919 Spanish influenza pandemic: mechanisms of psychosis risk

AP Kępińska, CO Iyegbe, AC Vernon, R Yolken… - Frontiers in …, 2020 - frontiersin.org
Associations between influenza infection and psychosis have been reported since the
eighteenth century, with acute “psychoses of influenza” documented during multiple …

Maternal immune activation and autism spectrum disorder: from rodents to nonhuman and human primates

M Careaga, T Murai, MD Bauman - Biological psychiatry, 2017 - Elsevier
A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or …

The role of maternal immune activation in the pathogenesis of autism: a review of the evidence, proposed mechanisms and implications for treatment

A Zawadzka, M Cieślik, A Adamczyk - International journal of molecular …, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disease that is characterized by a
deficit in social interactions and communication, as well as repetitive and restrictive …

Cross talk: the microbiota and neurodevelopmental disorders

JR Kelly, C Minuto, JF Cryan, G Clarke… - Frontiers in …, 2017 - frontiersin.org
Humans evolved within a microbial ecosystem resulting in an interlinked physiology. The gut
microbiota can signal to the brain via the immune system, the vagus nerve or other host …

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

D Mattei, A Ivanov, C Ferrai, P Jordan… - Translational …, 2017 - nature.com
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of
develo** psychiatric pathologies in later life. This link may be bridged by a defective …

Maternal inflammation and neurodevelopmental programming: a review of preclinical outcomes and implications for translational psychiatry

SB Gumusoglu, HE Stevens - Biological psychiatry, 2019 - Elsevier
Early disruptions to neurodevelopment are highly relevant to understanding both psychiatric
risk and underlying pathophysiology that can be targeted by new treatments. Much …

Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation

FS Mueller, J Scarborough, SM Schalbetter… - Molecular …, 2021 - nature.com
Infectious or noninfectious maternal immune activation (MIA) is an environmental risk factor
for psychiatric and neurological disorders with neurodevelopmental etiologies. Whilst there …