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The Global Expansion of Dengue: How Aedes aegypti Mosquitoes Enabled the First Pandemic Arbovirus
Dengue is an emerging viral disease principally transmitted by the Aedes (Stegomyia)
aegypti mosquito. It is one of the fastest-growing global infectious diseases, with 100–400 …
aegypti mosquito. It is one of the fastest-growing global infectious diseases, with 100–400 …
Human mobility and the global spread of infectious diseases: a focus on air travel
Greater human mobility, largely driven by air travel, is leading to an increase in the
frequency and reach of infectious disease epidemics. Air travel can rapidly connect any two …
frequency and reach of infectious disease epidemics. Air travel can rapidly connect any two …
Antibody-dependent enhancement of severe dengue disease in humans
For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to
enhance viral replication in vitro and severe disease in animal models. Although suspected …
enhance viral replication in vitro and severe disease in animal models. Although suspected …
A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction
SJF Kaptein, O Goethals, D Kiemel, A Marchand… - Nature, 2021 - nature.com
Dengue virus causes approximately 96 million symptomatic infections annually, manifesting
as dengue fever or occasionally as severe dengue,. There are no antiviral agents available …
as dengue fever or occasionally as severe dengue,. There are no antiviral agents available …
Dengue fever and insecticide resistance in Aedes mosquitoes in Southeast Asia: a review
Dengue fever is the most important mosquito-borne viral disease in Southeast Asia.
Insecticides remain the most effective vector control approach for Aedes mosquitoes. Four …
Insecticides remain the most effective vector control approach for Aedes mosquitoes. Four …
Impact of immune enhancement on Covid-19 polyclonal hyperimmune globulin therapy and vaccine development
The pandemic spread of a novel coronavirus–SARS coronavirus-2 (SARS-CoV-2) as a
cause of acute respiratory illness, named Covid-19, is placing the healthcare systems of …
cause of acute respiratory illness, named Covid-19, is placing the healthcare systems of …
Reconstruction of antibody dynamics and infection histories to evaluate dengue risk
As with many pathogens, most dengue infections are subclinical and therefore unobserved.
Coupled with limited understanding of the dynamic behaviour of potential serological …
Coupled with limited understanding of the dynamic behaviour of potential serological …
Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study
Background Oropouche virus is an arthropod-borne virus that has caused outbreaks of
Oropouche fever in central and South America since the 1950s. This study investigates …
Oropouche fever in central and South America since the 1950s. This study investigates …
Transmission dynamics of Zika virus in island populations: a modelling analysis of the 2013–14 French Polynesia outbreak
Between October 2013 and April 2014, more than 30,000 cases of Zika virus (ZIKV) disease
were estimated to have attended healthcare facilities in French Polynesia. ZIKV has also …
were estimated to have attended healthcare facilities in French Polynesia. ZIKV has also …
Benefits and risks of the Sanofi-Pasteur dengue vaccine: Modeling optimal deployment
The first approved dengue vaccine has now been licensed in six countries. We propose that
this live attenuated vaccine acts like a silent natural infection in priming or boosting host …
this live attenuated vaccine acts like a silent natural infection in priming or boosting host …