Alcohol-related liver disease (ALD): current perspectives on pathogenesis, therapeutic strategies, and animal models

X Hong, S Huang, H Jiang, Q Ma, J Qiu… - Frontiers in …, 2024‏ - frontiersin.org
Alcohol-related liver disease (ALD) is a major cause of morbidity and mortality worldwide. It
encompasses conditions such as fatty liver, alcoholic hepatitis, chronic hepatitis with liver …

[HTML][HTML] Alcohol Consumption and Autoimmune Diseases

S Terracina, B Caronti, M Lucarelli, S Francati… - International Journal of …, 2025‏ - mdpi.com
Alcohol is the second-most misused substance after tobacco. It has been identified as a
causal factor in more than 200 diseases and 5.3% of all deaths and is associated with …

Alleviation of alcoholic liver injury through composite postbiotics regulation of intestinal flora and promotion of bile acid metabolism

Q Peng, K Yang, Q Hou, H Zheng, X Zheng, G **e - Food Bioscience, 2024‏ - Elsevier
Alcoholic liver disease (ALD) arises from chronic alcohol consumption, leading to liver
damage and gut microbiota disruption. Current clinical treatments, including …

Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis

AMC Overstreet, MK Burge, A Bellar, M McMullen… - medRxiv, 2024‏ - medrxiv.org
Background and aims Alcohol-associated hepatitis (AH) is the most life-threatening form of
alcohol-associated liver disease (ALD). AH is characterized by severe inflammation …

[HTML][HTML] Alpinetin Exhibits Antioxidant and Anti-Inflammatory Effects in C57BL/6 Mice with Alcoholic Liver Disease Induced by the Lieber–DeCarli Ethanol Liquid Diet

T Radosavljevic, M Brankovic, J Djuretić… - International Journal of …, 2024‏ - mdpi.com
Alcohol-associated liver disease (ALD) is a common non-communicable chronic liver
disease characterized by a spectrum of conditions ranging from steatosis and alcohol …

Alcoholic Extracts from the Ganoderma Lucidum Fermentation Product Alleviated Ethanol-Induced Liver Injury, Gut Leakiness, and Gut Dysbiosis in Mice

Z Zhao, X Ma, M Li, G Chen, L Qi, S Song, Z Li… - Plant Foods for Human …, 2025‏ - Springer
The hepatoprotective effect of the alcoholic extracts of Ganoderma lucidum fermentation
products (GFE) was investigated. C57BL/6 mice were pretreated with GFE for 7 days and …

[HTML][HTML] Alcohol Consumption and Breast and Ovarian Cancer Development: Molecular Pathways and Mechanisms

F Fanfarillo, B Caronti, M Lucarelli… - Current Issues in …, 2024‏ - pmc.ncbi.nlm.nih.gov
Alcohol consumption has been consistently linked to an increased risk of several cancers,
including breast and ovarian cancer. Despite substantial evidence supporting this …

Oxidized HMGB1 Adducts Unleash Inflammation in Alcohol-Associated Liver Disease

P Kumar, F Tacke - Cellular and Molecular Gastroenterology and …, 2024‏ - cmghjournal.org
Alcohol-associated liver disease (AALD) remains a significant clinical challenge, driving
morbidity and mortality on a global scale. 1, 2 The pathogenesis of AALD involves a …