A hitchhiker's guide through the cell: the world according to the capsids of alphaherpesviruses

K Döhner, MC Serrero, A Viejo-Borbolla… - Annual Review of …, 2024 - annualreviews.org
The nucleoplasm, the cytosol, the inside of virions, and again the cytosol comprise the world
in which the capsids of alphaherpesviruses encounter viral and host proteins that support or …

The role of nuclear pores and importins for herpes simplex virus infection

K Döhner, MC Serrero, B Sodeik - Current opinion in virology, 2023 - Elsevier
Highlights•Dynein and kinesin-1.•Importin α, importin β, nuclear pores, and
nucleoporins.•BoHV-1, HSV-1, PrV, and VZV.Microtubule transport and nuclear import are …

Structural basis for genome packaging, retention, and ejection in human cytomegalovirus

Z Li, J Pang, L Dong, X Yu - Nature Communications, 2021 - nature.com
How the human cytomegalovirus (HCMV) genome—the largest among human
herpesviruses—is packaged, retained, and ejected remains unclear. We present the in situ …

Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

J Zhen, J Chen, H Huang, S Liao, S Liu, Y Yuan… - Journal of …, 2024 - journals.asm.org
Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV) are
classified into the gammaherpesvirus subfamily of Herpesviridae, which stands out from its …

Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150

YT Liu, D Strugatsky, W Liu, ZH Zhou - Nature communications, 2021 - nature.com
Under the Baltimore nucleic acid-based virus classification scheme, the herpesvirus human
cytomegalovirus (HCMV) is a Class I virus, meaning that it contains a double-stranded DNA …

[HTML][HTML] The journey of herpesvirus capsids and genomes to the host cell nucleus

K Döhner, A Cornelius, MC Serrero, B Sodeik - Current opinion in virology, 2021 - Elsevier
Highlights•Herpesvirus capsid stabilization, capsid portal vertices and portal caps.•Getting
dynein-mediated capsid transport on microtubule roads.•The enigma of translocating from …

DNA-packing portal and capsid-associated tegument complexes in the tumor herpesvirus KSHV

D Gong, X Dai, J Jih, YT Liu, GQ Bi, R Sun, ZH Zhou - Cell, 2019 - cell.com
Assembly of Kaposi's sarcoma-associated herpesvirus (KSHV) begins at a bacteriophage-
like portal complex that nucleates formation of an icosahedral capsid with capsid-associated …

[HTML][HTML] The ins and outs of herpesviral capsids: divergent structures and assembly mechanisms across the three subfamilies

EB Draganova, J Valentin, EE Heldwein - Viruses, 2021 - mdpi.com
Human herpesviruses, classified into three subfamilies, are double-stranded DNA viruses
that establish lifelong latent infections within most of the world's population and can cause …

Structures of capsid and capsid-associated tegument complex inside the Epstein–Barr virus

W Liu, Y Cui, C Wang, Z Li, D Gong, X Dai, GQ Bi… - Nature …, 2020 - nature.com
As the first discovered human cancer virus, Epstein–Barr virus (EBV) causes Burkitt's
lymphoma and nasopharyngeal carcinoma. Isolating virions for determining high-resolution …

CryoEM structure of the tegumented capsid of Epstein-Barr virus

Z Li, X Zhang, L Dong, J Pang, M Xu, Q Zhong… - Cell research, 2020 - nature.com
Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis and has been
shown to be closely associated with various malignancies. Here, we present a complete …