Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

Conductive polymers: opportunities and challenges in biomedical applications

T Nezakati, A Seifalian, A Tan, AM Seifalian - Chemical reviews, 2018 - ACS Publications
Research pertaining to conductive polymers has gained significant traction in recent years,
and their applications range from optoelectronics to material science. For all intents and …

The protein corona and its effects on nanoparticle-based drug delivery systems

H Li, Y Wang, Q Tang, D Yin, C Tang, E He, L Zou… - Acta biomaterialia, 2021 - Elsevier
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …

Protein corona: a new approach for nanomedicine design

VH Nguyen, BJ Lee - International journal of nanomedicine, 2017 - Taylor & Francis
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

H Arami, A Khandhar, D Liggitt… - Chemical Society …, 2015 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been extensively used during the last two decades,
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

C Corbo, R Molinaro, A Parodi… - …, 2016 - Taylor & Francis
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …

Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities

AA Ashkarran, H Gharibi, E Voke, MP Landry… - Nature …, 2022 - nature.com
Robust characterization of the protein corona—the layer of proteins that spontaneously
forms on the surface of nanoparticles immersed in biological fluids—is vital for prediction of …

Biological identity of nanoparticles in vivo: clinical implications of the protein corona

G Caracciolo, OC Farokhzad, M Mahmoudi - Trends in biotechnology, 2017 - cell.com
Despite the advances in biomedical applications of nanoparticle (NP) and numerous
publications, few NPs have made it to clinical trials and even fewer have reached clinical …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X **, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …