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Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …
the last five decades as they show enormous potential for many biomedical applications …
Conductive polymers: opportunities and challenges in biomedical applications
Research pertaining to conductive polymers has gained significant traction in recent years,
and their applications range from optoelectronics to material science. For all intents and …
and their applications range from optoelectronics to material science. For all intents and …
The protein corona and its effects on nanoparticle-based drug delivery systems
H Li, Y Wang, Q Tang, D Yin, C Tang, E He, L Zou… - Acta biomaterialia, 2021 - Elsevier
In most cases, once nanoparticles (NPs) enter the blood, their surface is covered by
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …
biological molecules, especially proteins, forming a so-called protein corona (PC). As a …
Protein corona: a new approach for nanomedicine design
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence
AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …
disease in incidence. Despite significant worldwide investment in research, cancer remains …
In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles
Iron oxide nanoparticles (IONPs) have been extensively used during the last two decades,
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …
The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …
where they circulate until they reach the target tissue. The ligand on the NP surface …
Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities
Robust characterization of the protein corona—the layer of proteins that spontaneously
forms on the surface of nanoparticles immersed in biological fluids—is vital for prediction of …
forms on the surface of nanoparticles immersed in biological fluids—is vital for prediction of …
Biological identity of nanoparticles in vivo: clinical implications of the protein corona
Despite the advances in biomedical applications of nanoparticle (NP) and numerous
publications, few NPs have made it to clinical trials and even fewer have reached clinical …
publications, few NPs have made it to clinical trials and even fewer have reached clinical …
The role of protein corona on nanodrugs for organ-targeting and its prospects of application
S Wang, J Zhang, H Zhou, YC Lu, X **, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …
to deliver drugs to reach their destination more effectively due to their unique properties and …