Data-driven multiscale computational models of cortical and subcortical regions
S Ramaswamy - Current opinion in neurobiology, 2024 - Elsevier
Data-driven computational models of neurons, synapses, microcircuits, and mesocircuits
have become essential tools in modern brain research. The goal of these multiscale models …
have become essential tools in modern brain research. The goal of these multiscale models …
Large-Scale Mechanistic Models of Brain Circuits with Biophysically and Morphologically Detailed Neurons
Understanding the brain requires studying its multiscale interactions from molecules to
networks. The increasing availability of large-scale datasets detailing brain circuit …
networks. The increasing availability of large-scale datasets detailing brain circuit …
Unsupervised classification of brain-wide axons reveals the presubiculum neuronal projection blueprint
DW Wheeler, S Banduri, S Sankararaman… - Nature …, 2024 - nature.com
We present a quantitative strategy to identify all projection neuron types from a given region
with statistically different patterns of anatomical targeting. We first validate the technique with …
with statistically different patterns of anatomical targeting. We first validate the technique with …
[LLIBRE][B] Neuromorphic Engineering: The Scientist's, Algorithms Designer's and Computer Architect's Perspectives on Brain-Inspired Computing
EE Tsur - 2021 - taylorfrancis.com
The brain is not a glorified digital computer. It does not store information in registers, and it
does not mathematically transform mental representations to establish perception or …
does not mathematically transform mental representations to establish perception or …
Simulations of cortical networks using spatially extended conductance‐based neuronal models
Abstract The Hodgkin–Huxley model of action potential generation and propagation,
published in the Journal of Physiology in 1952, initiated the field of biophysically detailed …
published in the Journal of Physiology in 1952, initiated the field of biophysically detailed …
[HTML][HTML] Biophysically detailed forward modeling of the neural origin of EEG and MEG signals
Electroencephalography (EEG) and magnetoencephalography (MEG) are among the most
important techniques for non-invasively studying cognition and disease in the human brain …
important techniques for non-invasively studying cognition and disease in the human brain …
Intracortical microstimulation pulse waveform and frequency recruits distinct spatiotemporal patterns of cortical neuron and neuropil activation
Objective. Neural prosthetics often use intracortical microstimulation (ICMS) for sensory
restoration. To restore natural and functional feedback, we must first understand how …
restoration. To restore natural and functional feedback, we must first understand how …
Highlights from the era of open source web-based tools
High digital connectivity and a focus on reproducibility are contributing to an open science
revolution in neuroscience. Repositories and platforms have emerged across the whole …
revolution in neuroscience. Repositories and platforms have emerged across the whole …
Modeling and simulation of rat non-barrel somatosensory cortex. part i: Modeling anatomy
MW Reimann, S Bolaños-Puchet, JD Courcol… - bioRxiv, 2022 - biorxiv.org
The function of the neocortex is fundamentally determined by its repeating microcircuit motif,
but also by its rich, hierarchical, interregional structure with a highly specific laminar …
but also by its rich, hierarchical, interregional structure with a highly specific laminar …
[HTML][HTML] The dark path to eternal life: Machiavellianism predicts approval of mind upload technology
M Laakasuo, M Repo, M Drosinou, A Berg… - Personality and …, 2021 - Elsevier
Mind upload, making a digital copy of one's brain, is a part of the transhumanistic dream of
eternal life and the end of suffering. It is also perceived as a viable route toward artificial …
eternal life and the end of suffering. It is also perceived as a viable route toward artificial …