[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection

BA Khalil, NM Elemam, AA Maghazachi - Computational and structural …, 2021 - Elsevier
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

The host immune response in respiratory virus infection: balancing virus clearance and immunopathology

AH Newton, A Cardani, TJ Braciale - Seminars in immunopathology, 2016 - Springer
The respiratory tract is constantly exposed to the external environment, and therefore, must
be equipped to respond to and eliminate pathogens. Viral clearance and resolution of …

Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19

Y Yang, C Shen, J Li, J Yuan, J Wei, F Huang… - Journal of Allergy and …, 2020 - Elsevier
Background The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 was first reported in Wuhan, December 2019, and …

Exuberant elevation of IP-10, MCP-3 and IL-1ra during SARS-CoV-2 infection is associated with disease severity and fatal outcome

Y Yang, C Shen, J Li, J Yuan, M Yang, F Wang, G Li… - MedRxiv, 2020 - medrxiv.org
The outbreak of Coronavirus Disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, December 2019 …

[PDF][PDF] Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury

Y Liu, C Zhang, F Huang, Y Yang, F Wang… - National Science …, 2020 - academic.oup.com
A recent outbreak of pneumonia in Wuhan, China was found to be caused by a 2019 novel
coronavirus (2019-nCoV or SARS-CoV-2 or HCoV-19). We previously reported the clinical …

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury

P Yang, H Gu, Z Zhao, W Wang, B Cao, C Lai… - Scientific reports, 2014 - nature.com
Since March 2013, the emergence of an avian-origin influenza A (H7N9) virus has raised
concern in China. Although most infections resulted in respiratory illness, some severe …

The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …

CXCL10 chemokine: a critical player in RNA and DNA viral infections

NM Elemam, IM Talaat, AA Maghazachi - Viruses, 2022 - mdpi.com
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …

Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury

F Huang, C Zhang, Q Liu, Y Zhao, Y Zhang… - PLoS …, 2020 - journals.plos.org
Infection with avian influenza A H5N1 virus results in acute lung injury (ALI) and has a high
mortality rate (52.79%) because there are limited therapies available for treatment. Drug …

Angiotensin II plasma levels are linked to disease severity and predict fatal outcomes in H7N9-infected patients

F Huang, J Guo, Z Zou, J Liu, B Cao, S Zhang… - Nature …, 2014 - nature.com
Abstract A novel influenza A (H7N9) virus of avian origin emerged in eastern China in the
spring of 2013. This virus causes severe disease in humans, including acute and often lethal …