Insect fat body: energy, metabolism, and regulation
The fat body plays major roles in the life of insects. It is a dynamic tissue involved in multiple
metabolic functions. One of these functions is to store and release energy in response to the …
metabolic functions. One of these functions is to store and release energy in response to the …
Drosophila tools and assays for the study of human diseases
Many of the internal organ systems of Drosophila melanogaster are functionally analogous
to those in vertebrates, including humans. Although humans and flies differ greatly in terms …
to those in vertebrates, including humans. Although humans and flies differ greatly in terms …
Lipid droplets: a unified view of a dynamic organelle
Lipid droplets form the main lipid store in eukaryotic cells. Although all cells seem to be able
to generate lipid droplets, their biogenesis, regulatory mechanisms and interactions with …
to generate lipid droplets, their biogenesis, regulatory mechanisms and interactions with …
A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis
Sleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is
achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial …
achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial …
Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
DL Brasaemle - Journal of lipid research, 2007 - ASBMB
The majority of eukaryotic cells synthesize neutral lipids and package them into cytosolic
lipid droplets. In vertebrates, triacylglycerol-rich lipid droplets of adipocytes provide a major …
lipid droplets. In vertebrates, triacylglycerol-rich lipid droplets of adipocytes provide a major …
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
The PAT family of lipid droplet proteins includes 5 members in mammals: perilipin, adipose
differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3–12, and …
differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3–12, and …
Methods for studying metabolism in Drosophila
Recent research using Drosophila melanogaster has seen a resurgence in studies of
metabolism and physiology. This review focuses on major methods used to conduct this …
metabolism and physiology. This review focuses on major methods used to conduct this …
Not just fat: the structure and function of the lipid droplet
Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
[HTML][HTML] Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
S Grönke, A Mildner, S Fellert, N Tennagels, S Petry… - Cell metabolism, 2005 - cell.com
Energy homeostasis, a fundamental property of all organisms, depends on the ability to
control the storage and mobilization of fat, mainly triacylglycerols (TAG), in special organs …
control the storage and mobilization of fat, mainly triacylglycerols (TAG), in special organs …
Minireview: lipid droplets in lipogenesis and lipolysis
Organisms store energy for later use during times of nutrient scarcity. Excess energy is
stored as triacylglycerol in lipid droplets during lipogenesis. When energy is required, the …
stored as triacylglycerol in lipid droplets during lipogenesis. When energy is required, the …