The exceptionally rapid development of highly flexible, reusable artificial intelligence (AI)
models is likely to usher in newfound capabilities in medicine. We propose a new paradigm …

Large Language Models (LLMs) went from non-existent to ubiquitous in the machine
learning discourse within a few years. Due to the fast pace of the field, it is difficult to identify …

Genomic (DNA) sequences encode an enormous amount of information for gene regulation
and protein synthesis. Similar to natural language models, researchers have proposed …

The prediction of molecular phenotypes from DNA sequences remains a longstanding
challenge in genomics, often driven by limited annotated data and the inability to transfer …

The genome is a sequence that encodes the DNA, RNA, and proteins that orchestrate an
organism's function. We present Evo, a long-context genomic foundation model with a …

Large Language Models (LLMs) have emerged as a transformative power in enhancing
natural language comprehension, representing a significant stride toward artificial general …

Abstract ChatGPT, GPT-4, and Bard are highly advanced natural language process–based
computer programs (chatbots) that simulate and process human conversation in written or …

Enzymes can be engineered at the level of their amino acid sequences to optimize key
properties such as expression, stability, substrate range, and catalytic efficiency─ or even to …

Recent years have seen a phenomenal rise in the performance and applications of
transformer neural networks. The family of transformer networks, including Bidirectional …

Large language models (LLMs) are having transformative impacts across a wide range of
scientific fields, particularly in the biomedical sciences. Just as the goal of natural language …