Achieving complete understanding of any living thing inevitably requires thorough analysis
of both its anatomic and dynamic properties. Live-cell imaging experiments carried out to …

In recent years, the deluge of complicated molecular and cellular microscopic images
creates compelling challenges for the image computing community. There has been an …

Particle tracking is of key importance for quantitative analysis of intracellular dynamic
processes from time-lapse microscopy image data. Because manually detecting and …

The light microscope has long been used to document the localization of fluorescent
molecules in cell biology research. With advances in digital cameras and the discovery and …

Mitochondria display complex morphology and movements, which complicates their
segmentation and tracking in time-lapse images. Here, we introduce Mitometer, an algorithm …

The past decade has seen an unprecedented data explosion in biology. It has become
evident that in order to take full advantage of the potential wealth of information hidden in the …

Quantitative analysis of biological image data generally involves the detection of many
subresolution spots. Especially in live cell imaging, for which fluorescence microscopy is …

During mitosis in most eukaryotic cells, chromosomes align and form a metaphase plate
halfway between the spindle poles, about which they exhibit oscillatory movement. These …

Advances in optical microscopy, biosensors and cell culturing technologies have
transformed live cell imaging. Thanks to these advances live cell imaging plays an …

In todays health care, imaging plays an important role throughout the entire clinical process
from diagnostics and treatment planning to surgical procedures and follow up studies. Since …