More than 80 studies have reported lowered blood pressure after dietary calcium
enrichment in experimental models of hypertension. The evidence presented here suggests …

The elevated arterial pressure of chronic hypertension (HT) is caused by increased total
peripheral vascular resistance (TPVR). Hemodynamically, therefore, HT is the result of …

Arteries of hypertensive animals have a greater mass of smooth muscle than those of
normotensive controls. We examined the contribution of smooth muscle cell hypertrophy and …

Discussion DR. DAVID A. MCCARRON (Professor of Medicine and Co-head of the Division
of Nephrology and Hypertension, and Director ofthe National Dai, y Board Instil ute for …

Calcium currents were recorded during whole-cell voltage clamp in cultured azygos venous
muscle cells from 1-3-day-old normotensive Wistar-Kyoto rats (WKY) and spontaneously …

The blood pressure of the spontaneously hypertensive rat (SHR) is influenced by the Ca2+
content of its diet. As the SHR's greater dependence on dietary calcium may reflect a defect …

A paradigm is developed for identifying the genes (and the biochemical-physiological traits
for which the genes code) that cause differences in blood pressure in inbred strains of rats. A …

Calcium handling by erythrocyte membranes was compared in genetically hypertensive
(SHR) and normotensive (WKR) rats by direct measurement of calcium binding, passive …

We have utilized multinuclear NMR spectroscopy to examine the relationship between
cytosolic free Ca2+ ([Ca2+] in), free Mg2+ ([Mg2+] in) and intracellular Na+ ([Na+] in) levels …

The greater efficacy of organic channel blockers in lowering peripheral resistance and blood
pressure in hypertensive subjects has been suggested to be the result of augmented …