Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain
A central challenge of neuroscience is to elucidate how brain function supports
consciousness. Here, we combine the specificity of focal deep brain stimulation with fMRI …
consciousness. Here, we combine the specificity of focal deep brain stimulation with fMRI …
The thalamus in perioperative neurocognitive disorders
Thalamus function and structure are known predictors of individual differences in the risk of
age-related neurocognitive disorders (NCD), such as dementia. However, to date, little is …
age-related neurocognitive disorders (NCD), such as dementia. However, to date, little is …
Neural Network Mechanisms Underlying General Anesthesia: Cortical and Subcortical Nuclei
Y Hu, Y Wang, L Zhang, M Luo, Y Wang - Neuroscience Bulletin, 2024 - Springer
General anesthesia plays a significant role in modern medicine. However, the precise
mechanism of general anesthesia remains unclear, posing a key scientific challenge in …
mechanism of general anesthesia remains unclear, posing a key scientific challenge in …
Influence of clinical and genetic factors on propofol dose requirements: A genome-wide association study
S Ahlström, P Reiterä, R Jokela, KT Olkkola… - …, 2024 - ingentaconnect.com
Background: Propofol is a widely used intravenous hypnotic. Dosing is based mostly on
weight, with great interindividual variation in consumption. Suggested factors affecting …
weight, with great interindividual variation in consumption. Suggested factors affecting …
Propofol disrupts the functional core-matrix architecture of the thalamus in humans
Research into the role of thalamocortical circuits in anesthesia-induced unconsciousness is
difficult due to anatomical and functional complexity. Prior neuroimaging studies have …
difficult due to anatomical and functional complexity. Prior neuroimaging studies have …
The relationship of bispectral index values to conscious state: an analysis of two volunteer cohort studies
Background The ability of current depth-of-anaesthesia monitors to differentiate subtle
changes in the conscious state has not been well characterised. We examine the variability …
changes in the conscious state has not been well characterised. We examine the variability …
SESN2 attenuates sevoflurane-induced cognitive impairment and neuroinflammation in rats
L Sun, Y Li, D Wang, X Hong - Experimental Brain Research, 2024 - Springer
Long-term use of sevoflurane, an inhalation anesthetic, could negatively impact cognitive
function. Current studies have suggested that cognitive impairment induced by sevoflurane …
function. Current studies have suggested that cognitive impairment induced by sevoflurane …
Local Orchestration of Global Functional Patterns Supporting Loss and Restoration of Consciousness in the Primate Brain
A central challenge of neuroscience is to elucidate how the orchestration of brain function is
modulated by different states of consciousness. Here, we investigate the link between …
modulated by different states of consciousness. Here, we investigate the link between …
Study on the antidepressant activity of (2R, 6R; 2S, 6S)-Hydroxynorketamine (HNK) and its derivatives
D Zang, X Yang, H Wang, Z Li, Y Ma, J Liu, X Mei, S Li… - Clinics, 2024 - SciELO Brasil
Objective: This study mainly explores (2R, 6R; 2S, 6S)-HNK and its compounds whether
there are antidepressant effects. Methods: Four HNK compounds were obtained from 2 …
there are antidepressant effects. Methods: Four HNK compounds were obtained from 2 …
[HTML][HTML] The Effect of Sevoflurane and Propofol on the Status of Renal Complications in Traumatic Injury Patients Following Laminectomy Surgery
Objectives: Laminectomy is one of the most prevalent back surgeries. Considering the
importance of controlling and minimizing surgical complications, this study was conducted to …
importance of controlling and minimizing surgical complications, this study was conducted to …