Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology

A Potron, L Poirel, P Nordmann - International journal of antimicrobial …, 2015 - Elsevier
Multidrug resistance is quite common among non-fermenting Gram-negative rods, in
particular among clinically relevant species including Pseudomonas aeruginosa and …

Nationwide surveillance of clinical carbapenem-resistant Enterobacteriaceae (CRE) strains in China

R Zhang, L Liu, H Zhou, EW Chan, J Li, Y Fang, Y Li… - …, 2017 - thelancet.com
The increasing incidence of carbapenem-resistant Enterobacteriaceae (CRE)-mediated
hospital infections in China prompted a need to investigate the genetic basis of emergence …

A global view on carbapenem-resistant Acinetobacter baumannii

C Müller, S Reuter, J Wille, K Xanthopoulou, D Stefanik… - MBio, 2023 - journals.asm.org
To give an update on the molecular epidemiology and global distribution of carbapenemase
encoding genes, we subjected 313 carbapenem-resistant Acinetobacter baumannii isolated …

Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - pmc.ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

“Stormy waters ahead”: global emergence of carbapenemases

G Patel, RA Bonomo - Frontiers in microbiology, 2013 - frontiersin.org
Carbapenems, once considered the last line of defense against of serious infections with
Enterobacteriaceae, are threatened with extinction. The increasing isolation of carbapenem …

Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance

AP Johnson, N Woodford - Journal of medical …, 2013 - microbiologyresearch.org
The rapidity with which new types of antibiotic resistance can disseminate globally following
their initial emergence or recognition is exemplified by the novel carbapenemase New Delhi …

The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace

I Roca, P Espinal, X Vila-Farrés, J Vila - Frontiers in microbiology, 2012 - frontiersin.org
During the past few decades Acinetobacter baumannii has evolved from being a commensal
dweller of health-care facilities to constitute one of the most annoying pathogens …

Insertion Sequence IS26 Reorganizes Plasmids in Clinically Isolated Multidrug-Resistant Bacteria by Replicative Transposition

S He, AB Hickman, AM Varani, P Siguier, M Chandler… - MBio, 2015 - journals.asm.org
ABSTRACT Carbapenemase-producing Enterobacteriaceae (CPE), which are resistant to
most or all known antibiotics, constitute a global threat to public health. Transposable …

Mobile genetic elements in Acinetobacter antibiotic‐resistance acquisition and dissemination

HR Noel, JR Petrey, LD Palmer - … of the New York Academy of …, 2022 - Wiley Online Library
Pathogenic Acinetobacter species, most notably Acinetobacter baumannii, are a significant
cause of healthcare‐associated infections worldwide. Acinetobacter infections are of …