Evolution favored individuals with superior cognitive and physical abilities under conditions
of limited food sources, and brain function can therefore be optimized by intermittent dietary …

Age-associated hyper-inflammation or “inflamm-aging” has been linked to the development
of chronic diseases and characterized as an unavoidable aspect of aging. However, the …

Preconditioning is a phenomenon in which brief episodes of a sublethal insult induce robust
protection against subsequent lethal injuries. Preconditioning has been observed in multiple …

Stroke-induced cognitive impairments affect the long-term quality of life. High-intensity
interval training (HIIT) is now considered a promising strategy to enhance cognitive …

Cells have evolved multiple and sophisticated stress response mechanisms aiming to
prevent macromolecular (including proteins, lipids, and nucleic acids) damage and to …

It is well established that physical exercise can exert neuroprotection both in clinical settings
and animal experiments. A series of studies have demonstrated that physical exercise may …

A collection of metabolic disorders and neurodegenerative diseases linked to oxidative
stress and neuroinflammation frequently affect postmenopausal women or estrogen …

Ischemia induces physiological alterations in neurons that lead to cell death. This study
investigated the effects of pre-ischemic exercise on CA3 neurons. Rats were divided into …

Preconditioning exercise can exert neuroprotective effects after stroke. However, the
mechanism underlying these neuroprotective effects by preconditioning exercise remains …

Individual tissues have significantly different resistance to ischemia–reperfusion damage.
There is still no adequate treatment for the consequences of ischemia–reperfusion damage …