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Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology
JG Kiang, GC Tsokos - Pharmacology & therapeutics, 1998 - Elsevier
Heat shock proteins (HSPs) are detected in all cells, prokaryotic and eukaryotic. In vivo and
in vitro studies have shown that various stressors transiently increase production of HSPs as …
in vitro studies have shown that various stressors transiently increase production of HSPs as …
Role of heat shock proteins in protection from and pathogenesis of infectious diseases
U Zügel, SHE Kaufmann - Clinical Microbiology Reviews, 1999 - journals.asm.org
Increased synthesis of heat shock proteins (hsp) occurs in prokaryotic and eukaryotic cells
when they are exposed to stress. By increasing their hsp content, cells protect themselves …
when they are exposed to stress. By increasing their hsp content, cells protect themselves …
Heat shock proteins as regulators of the immune response
AG Pockley - The lancet, 2003 - thelancet.com
Until recently, heat shock proteins (also known as heat stress proteins) have mostly been
regarded as intracellular molecules that mediate a range of essential housekee** and …
regarded as intracellular molecules that mediate a range of essential housekee** and …
Heat-shock proteins induce T-cell regulation of chronic inflammation
Immune responses to certain heat-shock proteins (HSPs) develop in almost all inflammatory
diseases; however, the significance of such responses is only now becoming clear. In …
diseases; however, the significance of such responses is only now becoming clear. In …
Heat shock proteins and the immune response
SHE Kaufmann - Immunology today, 1990 - cell.com
Heat shock proteins (HSPs) or stress proteins are produced by prokaryotic and eukaryotic
cells in response to a variety of insults. After this original definition, it has become incre …
cells in response to a variety of insults. After this original definition, it has become incre …
Identification of a site in glutamate receptor subunits that controls calcium permeability
The neurotransmitter glutamate mediates excitatory synaptic transmission throughout the
brain. A family of genes encoding subunits of the non-N-methyl-D-aspartate (non-NMDA) …
brain. A family of genes encoding subunits of the non-N-methyl-D-aspartate (non-NMDA) …
IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis
E Lubberts, LAB Joosten, B Oppers… - The Journal of …, 2001 - journals.aai.org
T cell IL-17 displays proinflammatory properties and is expressed in the synovium of patients
with rheumatoid arthritis. Its contribution to the arthritic process has not been identified. Here …
with rheumatoid arthritis. Its contribution to the arthritic process has not been identified. Here …
Association between the 65-kilodalton heat shock protein, Streptococcus sanguis, and the corresponding antibodies in Behcet's syndrome
T Lehner, E Lavery, R Smith, R Van Der Zee… - Infection and …, 1991 - journals.asm.org
The etiology of Behcet's syndrome (BS) is unknown, but a number of streptococcal species
have been implicated. A hypothesis was postulated that a shared antigen, such as a stress …
have been implicated. A hypothesis was postulated that a shared antigen, such as a stress …
Give us this day our daily germs
GAW Rook, JL Stanford - Immunology today, 1998 - cell.com
Modern vaccinations, fear of germs and obsession with hygiene are depriving the immune
system of the information input upon which it is dependent. This fails to maintain the correct …
system of the information input upon which it is dependent. This fails to maintain the correct …
Heat shock proteins, inflammation, and cardiovascular disease
AG Pockley - Circulation, 2002 - ahajournals.org
molecules would adversely influence protein homeostasis and a variety of intracellular
functions. One mechanism by which HSF1 activity is negatively regulated is by hsp70 …
functions. One mechanism by which HSF1 activity is negatively regulated is by hsp70 …