Pharmacodynamics material basis and effective mechanisms are the two main issues to
decipher the mechnisms of action of Traditional Chinese medicines (TCMs) for the treatment …

Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time …

Background Huai Hua San (HHS), a famous Traditional Chinese Medicine (TCM) formula,
has been widely applied in treating ulcerative colitis (UC). However, the interaction of …

Objective: Curcumin is a plant polyphenol extracted from the Chinese herb turmeric. It was
found that curcumin has good anti-cancer properties in a variety of cancers, but the exact …

Background Huachansu (HCS), a known Chinese patent drug extracted from the Chinese
toad skin, is frequently used for the treatment of various advanced cancers, especially …

The interplay between life sciences and advancing technology drives a continuous cycle of
chemical data growth; these data are most often stored in open or partially open databases …

Background With the increasing development of biotechnology and informatics technology,
publicly available data in chemistry and biology are undergoing explosive growth. Such …

The neuroinflammatory response after intracerebral hemorrhage (ICH) causes a large
amount of neuronal loss, and inhibiting the inflammatory response can improve the …

Background Rheumatoid arthritis (RA) is currently an autoimmune inflammatory disease
with an unclear pathogenesis. Fibroblast-like synoviocytes (FLSs) have tumor-like …

Traditional Chinese medicine (TCM) has long been used in the clinical treatment of coronary
heart disease (CHD). TCM is characterized by syndrome-based medication, which is, using …