Insights on molecular mechanisms of chondrocytes death in osteoarthritis
E Charlier, B Relic, C Deroyer, O Malaise… - International journal of …, 2016 - mdpi.com
Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …
Pathophysiological perspective of osteoarthritis
Osteoarthritis (OA) is the most well-known degenerative disease among the geriatric and is
a main cause of significant disability in daily living. It has a multifactorial etiology and is …
a main cause of significant disability in daily living. It has a multifactorial etiology and is …
Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis
T Hayami, M Pickarski, Y Zhuo, GA Wesolowski… - Bone, 2006 - Elsevier
Osteoarthritis (OA) is a chronic joint disease characterized by cartilage destruction,
subchondral bone sclerosis, and osteophyte formation. Subchondral bone stiffness has …
subchondral bone sclerosis, and osteophyte formation. Subchondral bone stiffness has …
Biomarkers of joint damage in osteoarthritis: current status and future directions
R Kumavat, V Kumar, R Malhotra… - Mediators of …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a disease of the whole joint organ, characterized by the loss of
cartilage, and structural changes in bone including the formation of osteophytes, causing …
cartilage, and structural changes in bone including the formation of osteophytes, causing …
Engineering of gradient osteochondral tissue: From nature to lab
S Ansari, S Khorshidi, A Karkhaneh - Acta biomaterialia, 2019 - Elsevier
The osteochondral tissue is an interface between two distinct tissues: articular cartilage and
bone. These two tissues are significantly diverse with regard to their chemical compositions …
bone. These two tissues are significantly diverse with regard to their chemical compositions …
A systematic review of the relationship between subchondral bone features, pain and structural pathology in peripheral joint osteoarthritis
AJ Barr, TM Campbell, D Hopkinson… - Arthritis research & …, 2015 - Springer
Introduction Bone is an integral part of the osteoarthritis (OA) process. We conducted a
systematic literature review in order to understand the relationship between non …
systematic literature review in order to understand the relationship between non …
The effect of ageing and osteoarthritis on the mechanical properties of cartilage and bone in the human knee joint
Osteoarthritis is traditionally associated with cartilage degeneration although is now widely
accepted as a whole-joint disease affecting the entire osteochondral unit; however site …
accepted as a whole-joint disease affecting the entire osteochondral unit; however site …
Clinical implications of macrophage dysfunction in the development of osteoarthritis of the knee
J **e, Z Huang, X Yu, L Zhou, F Pei - Cytokine & growth factor reviews, 2019 - Elsevier
Osteoarthritis (OA) is the most common form of arthritic disease, leading to disability and
impaired quality of life and no curative treatments exist. Increasing evidence indicates that …
impaired quality of life and no curative treatments exist. Increasing evidence indicates that …
[HTML][HTML] Altered cartilage mechanics and histology in knee osteoarthritis: relation to clinical assessment (ICRS Grade)
RU Kleemann, D Krocker, A Cedraro, J Tuischer… - Osteoarthritis and …, 2005 - Elsevier
OBJECTIVE: Substantial changes in articular cartilage composition and mechanical
properties occur during the development of osteoarthritis (OA). While softening in the initial …
properties occur during the development of osteoarthritis (OA). While softening in the initial …
Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis
M Bellido, L Lugo, JA Roman-Blas, S Castañeda… - Arthritis research & …, 2010 - Springer
Introduction Osteoporosis (OP) increases cartilage damage in a combined rabbit model of
OP and osteoarthritis (OA). Accordingly, we assessed whether microstructure impairment at …
OP and osteoarthritis (OA). Accordingly, we assessed whether microstructure impairment at …