Matrix metalloproteinases as therapeutic targets in breast cancer
MJ Kwon - Frontiers in Oncology, 2023 - frontiersin.org
Matrix metalloproteinases (MMPs) are the most prominent proteinases involved in
tumorigenesis. They were initially recognized to promote tumor progression by remodeling …
tumorigenesis. They were initially recognized to promote tumor progression by remodeling …
Mesenchymal stromal cells (MSCs): an ally of B-cell acute lymphoblastic leukemia (B-ALL) cells in disease maintenance and progression within the bone marrow …
Simple Summary B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric
cancer. Even though the cure rate actually exceeds 85%, the prognosis of …
cancer. Even though the cure rate actually exceeds 85%, the prognosis of …
CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer
Currently, breast cancer (BRCA) has become the most common cancer in the world, whose
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
pathological mechanism is complex. Among its subtypes, triple-negative breast cancer …
Composite feature selection using deep ensembles
In many real world problems, features do not act alone but in combination with each other.
For example, in genomics, diseases might not be caused by any single mutation but require …
For example, in genomics, diseases might not be caused by any single mutation but require …
Emerging intrinsic therapeutic targets for metastatic breast cancer
Simple Summary Metastasis is the root cause of cancer death, responsible for roughly 90%
of all cancer-related fatalities. Therefore, treating metastatic cancer is essential for optimal …
of all cancer-related fatalities. Therefore, treating metastatic cancer is essential for optimal …
MMP12 serves as an immune cell–related marker of disease status and prognosis in lung squamous cell carcinoma
W Zhang, GS Li, XY Gan, ZG Huang, RQ He, H Huang… - PeerJ, 2023 - peerj.com
Background Worldwide, lung squamous cell carcinoma (LUSC) has wreaked havoc on
humanity. Matrix metallopeptidase 12 (MMP12) plays an essential role in a variety of …
humanity. Matrix metallopeptidase 12 (MMP12) plays an essential role in a variety of …
Plasma Levels of Metalloproteinase 3 (MMP-3) and Metalloproteinase 7 (MMP-7) as New Candidates for Tumor Biomarkers in Diagnostic of Breast Cancer Patients
P Ławicki, P Malinowski, J Motyka, M Ławicki… - Journal of Clinical …, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are a group of enzymes that mediate both physiological
and pathological processes such as carcinogenesis. The role of matrix metalloproteinase-3 …
and pathological processes such as carcinogenesis. The role of matrix metalloproteinase-3 …
[HTML][HTML] Both a hypoxia-inducible EYA3 and a histone acetyltransferase p300 function as coactivators of SIX5 to mediate tumorigenesis and cancer progression
C Yang, H Liu - Annals of Translational Medicine, 2022 - ncbi.nlm.nih.gov
Background The transcription partners of eyes absent homologs and sine oculis homeobox
homologs (EYA-SIX) contribute to tumorigenesis and progression of multiple cancers …
homologs (EYA-SIX) contribute to tumorigenesis and progression of multiple cancers …
Central centrifugal cicatricial alopecia in the adolescent population: an overview of available literature
V Palmer, M Valdebran - Life, 2023 - mdpi.com
Central centrifugal cicatricial alopecia (CCCA) is a lymphocytic scarring alopecia that
predominantly affects women of African descent. Recent studies have demonstrated …
predominantly affects women of African descent. Recent studies have demonstrated …
Loss of MMP-27 Predicts Mandibular Bone Invasion in Oral Squamous Cell Carcinoma
J Eichberger, F Weber, G Spanier, M Gerken… - Cancers, 2022 - mdpi.com
Simple Summary The growth of oral squamous cell carcinoma into the mandible poses
significant challenges to head and neck surgery. The resulting need for extensive …
significant challenges to head and neck surgery. The resulting need for extensive …