Sialic acid receptors of viruses

M Matrosovich, G Herrler, HD Klenk - … chemistry and biology II: tools and …, 2015 - Springer
Sialic acid linked to glycoproteins and gangliosides is used by many viruses as a receptor
for cell entry. These viruses include important human and animal pathogens, such as …

[HTML][HTML] NMR as a “gold standard” method in drug design and discovery

AH Emwas, K Szczepski, BG Poulson, K Chandra… - Molecules, 2020 - mdpi.com
Studying disease models at the molecular level is vital for drug development in order to
improve treatment and prevent a wide range of human pathologies. Microbial infections are …

Norovirus infectivity in humans and persistence in water

SR Seitz, JS Leon, KJ Schwab, GM Lyon… - Applied and …, 2011 - journals.asm.org
To examine the long-term infectivity of human norovirus in water, 13 study subjects were
challenged at different time points with groundwater spiked with the prototype human …

Carbon dots' antiviral functions against noroviruses

X Dong, MM Moyer, F Yang, YP Sun, L Yang - Scientific reports, 2017 - nature.com
This study reported the first assessment of carbon dots'(CDots) antiviral activity to human
norovirus virus-like-particles (VLPs), GI. 1 and GII. 4 VLPs. CDots with different surface …

Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine noroviruses

S Taube, JW Perry, K Yetming, SP Patel… - Journal of …, 2009 - journals.asm.org
Noroviruses are the major cause of nonbacterial gastroenteritis in humans. However, little is
known regarding the norovirus life cycle, including cell binding and entry. In contrast to …

Histo-blood group antigens: a common niche for norovirus and rotavirus

M Tan, X Jiang - Expert reviews in molecular medicine, 2014 - cambridge.org
Noroviruses (NoVs) and rotaviruses (RVs), the two most important causes of viral acute
gastroenteritis, are found to recognise histo-blood group antigens (HBGAs) as receptors or …

Bitter-sweet symphony: glycan–lectin interactions in virus biology

W Van Breedam, S Pöhlmann… - FEMS microbiology …, 2014 - academic.oup.com
Glycans are carbohydrate modifications typically found on proteins or lipids, and can act as
ligands for glycan-binding proteins called lectins. Glycans and lectins play crucial roles in …

Norovirus–host interaction: multi-selections by human histo-blood group antigens

M Tan, X Jiang - Trends in microbiology, 2011 - cell.com
The discovery of human histo-blood group antigens (HBGAs) as receptors or ligands of
noroviruses (NoVs) raises a question about the potential role of host factors in the evolution …

Environmental transmission of human noroviruses in shellfish waters

CJA Campos, DN Lees - Applied and environmental microbiology, 2014 - journals.asm.org
Human noroviruses (NoV) are the most common cause of epidemic gastroenteritis following
consumption of bivalve shellfish contaminated with fecal matter. NoV levels can be …

[HTML][HTML] Noroviral P particle: structure, function and applications in virus–host interaction

M Tan, P Fang, T Chachiyo, M **a, P Huang, Z Fang… - Virology, 2008 - Elsevier
Noroviruses are an important cause of epidemic acute gastroenteritis and the viruses
recognize human histo-blood group antigens (HBGAs) as receptors. The protruding (P) …