Regulation of the immune response by the aryl hydrocarbon receptor
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is
activated by small molecules provided by the diet, microorganisms, metabolism, and …
activated by small molecules provided by the diet, microorganisms, metabolism, and …
[HTML][HTML] Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review
JI Silverberg, M Boguniewicz, FJ Quintana… - Journal of Allergy and …, 2024 - Elsevier
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that has wide-
ranging roles, including regulation of inflammation and homeostasis. AhR is not a cell …
ranging roles, including regulation of inflammation and homeostasis. AhR is not a cell …
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
Disease tolerance is the ability of the host to reduce the effect of infection on host fitness.
Analysis of disease tolerance pathways could provide new approaches for treating …
Analysis of disease tolerance pathways could provide new approaches for treating …
Aryl hydrocarbon receptor promotes IL-10 expression in inflammatory macrophages through Src-STAT3 signaling pathway
J Zhu, L Luo, L Tian, S Yin, X Ma, S Cheng… - Frontiers in …, 2018 - frontiersin.org
The aryl hydrocarbon receptor (AhR) is an important immune regulator with a role in
inflammatory response. However, the role of AhR in IL-10 production by inflammatory …
inflammatory response. However, the role of AhR in IL-10 production by inflammatory …
An overview of aryl hydrocarbon receptor ligands in the Last two decades (2002–2022): A medicinal chemistry perspective
L Lin, Y Dai, Y **a - European Journal of Medicinal Chemistry, 2022 - Elsevier
The aryl hydrocarbon receptor (AhR), discovered 46 years ago, is a transcript factor member
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …
Aryl hydrocarbon receptor: The master regulator of immune responses in allergic diseases
F Riaz, F Pan, P Wei - Frontiers in Immunology, 2022 - frontiersin.org
The aryl hydrocarbon receptor (AhR) is a widely studied ligand-activated cytosolic
transcriptional factor that has been associated with the initiation and progression of various …
transcriptional factor that has been associated with the initiation and progression of various …
The AhR twist: ligand-dependent AhR signaling and pharmaco-toxicological implications
The aryl hydrocarbon receptor (AhR) is a transcription factor which is activated by diverse
compounds and regulates the expression of xenobiotic metabolism genes. Recent studies …
compounds and regulates the expression of xenobiotic metabolism genes. Recent studies …
[HTML][HTML] Unraveling the differential impact of PAHs and dioxin-like compounds on AKR1C3 reveals the EGFR extracellular domain as a critical determinant of the AHR …
C Vogeley, NC Sondermann, S Woeste… - Environment …, 2022 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs), dioxin-like compounds (DLCs) and structurally-
related environmental pollutants may contribute to the pathogenesis of various diseases and …
related environmental pollutants may contribute to the pathogenesis of various diseases and …
The aryl hydrocarbon receptor shapes monocyte transcriptional responses to interleukin-4 by prolonging STAT6 binding to promoters
Cytokines induce functional and metabolic adaptations in immune cells, typically through
transcriptional responses that can be influenced by other extracellular signals and by …
transcriptional responses that can be influenced by other extracellular signals and by …
Plant occurring flavonoids as modulators of the aryl hydrocarbon receptor
The aryl hydrocarbon receptor (AhR) is a transcription factor deeply implicated in health and
diseases. Historically identified as a sensor of xenobiotics and mainly toxic substances, AhR …
diseases. Historically identified as a sensor of xenobiotics and mainly toxic substances, AhR …