Most land plants are now known to be ancient polyploids that have rediploidized.
Diploidization involves many changes in genome organization that ultimately restore …

Aquaculture has made an enormous contribution to the world food production, especially to
the sustainable supply of animal proteins. The utility of diverse reproduction strategies in …

INTRODUCTION Protein-protein interactions play critical roles in biology, but the structures
of many eukaryotic protein complexes are unknown, and there are likely many interactions …

Zebrafish have become a popular organism for the study of vertebrate gene function,. The
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …

We have produced an mRNA expression time course of zebrafish development across 18
time points from 1 cell to 5 days post-fertilisation sampling individual and pools of embryos …

The hypothesis that the relatively large and complex vertebrate genome was created by two
ancient, whole genome duplications has been hotly debated, but remains unresolved. We …

Heart disease is the leading cause of death worldwide. Despite decades of research, most
heart pathologies have limited treatments, and often the only curative approach is heart …

An important mechanism for the evolution of phenotypic complexity, diversity and innovation,
and the origin of novel gene functions is the duplication of genes and entire genomes …

▪ Abstract Over 35 years ago, Susumu Ohno stated that gene duplication was the single
most important factor in evolution. He reiterated this point a few years later in proposing that …

Teleost fish, which roughly make up half of the extant vertebrate species, exhibit an amazing
level of biodiversity affecting their morphology, ecology and behaviour as well as many other …