IGF-binding proteins: why do they exist and why are there so many?

JB Allard, C Duan - Frontiers in endocrinology, 2018 - frontiersin.org
Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both
endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local …

IGF binding proteins in cancer: mechanistic and clinical insights

RC Baxter - Nature Reviews Cancer, 2014 - nature.com
The six members of the family of insulin-like growth factor (IGF) binding proteins (IGFBPs)
were originally characterized as passive reservoirs of circulating IGFs, but they are now …

A well-constrained estimate for the timing of the salmonid whole genome duplication reveals major decoupling from species diversification

DJ Macqueen, IA Johnston - Proceedings of the Royal …, 2014 - royalsocietypublishing.org
Whole genome duplication (WGD) is often considered to be mechanistically associated with
species diversification. Such ideas have been anecdotally attached to a WGD at the stem of …

Regulation of skeletal muscle growth in fish by the growth hormone–insulin-like growth factor system

EN Fuentes, JA Valdés, A Molina… - General and Comparative …, 2013 - Elsevier
The growth hormone (GH)-insulin-like growth factor (IGF) system is the key promoter of
growth in vertebrates; however, how this system modulates muscle mass in fish is just …

Stress and growth

B Sadoul, MM Vijayan - Fish physiology, 2016 - Elsevier
1. Introduction 2. A Conceptual Framework for Growth 2.1. The Dynamic Energy Budget
(DEB) Model for Growth 2.2. Myocyte Growth 3. Stress Effect on Energy Available for Growth …

Comparative evaluation of processed soybean meal (EnzoMealTM) vs. regular soybean meal as a fishmeal replacement in diets of rainbow trout (Oncorhynchus …

V Kumar, S Lee, BM Cleveland, N Romano, RS Lalgudi… - Aquaculture, 2020 - Elsevier
A 12-week feeding trial was conducted to compare low and high inclusions of conventional
soybean meal (SBM) or enzyme-treated SBM (Enzo) as fishmeal replacements in the diets …

Insulin-like growth factor signalling and its significance as a biomarker in fish and shellfish research

S Chandhini, B Trumboo, S Jose, T Varghese… - Fish Physiology and …, 2021 - Springer
The insulin-like growth factor signalling system comprises insulin-like growth factors, insulin-
like growth factor receptors and insulin-like growth factor-binding proteins. Along with the …

Insulin-like growth factor-binding proteins of teleost fishes

D Garcia de la Serrana, DJ Macqueen - Frontiers in Endocrinology, 2018 - frontiersin.org
The insulin-like growth factor (Igf) binding protein (Igfbp) family has a broad range of
physiological functions and a fascinating evolutionary history. This review focuses on the …

Somatotropic axis regulation unravels the differential effects of nutritional and environmental factors in growth performance of marine farmed fishes

J Pérez-Sánchez, P Simó-Mirabet… - Frontiers in …, 2018 - frontiersin.org
The Gh/Prl/Sl family has evolved differentially through evolution, resulting in varying
relationships between the somatotropic axis and growth rates within and across fish species …

Insight into the mechanisms of action of estrogen receptor β in the breast, prostate, colon, and CNS

P Dey, RPA Barros, M Warner, A Ström… - Journal of …, 2013 - jme.bioscientifica.com
Somatostatin (SS) and urotensin II (UII) are members of two families of structurally related
neuropeptides present in all vertebrates. They exert a large array of biological activities that …