Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Extracellular matrix is rich in biomolecules including structural proteins,
glycosaminoglycans, and small molecules that are important for the maintenance and repair …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Background The regeneration and repair of articular cartilage remains a major challenge for
clinicians and scientists due to the poor intrinsic healing of this tissue. Since cartilage …

Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

Craniofacial bone regeneration is a coupled process of angiogenesis and osteogenesis,
which, associated with infection, still remains a challenge in bone defects after trauma or …

Despite numerous studies on chondrogenesis, the repair of cartilage—particularly the
reconstruction of cartilage lacunae through an all-in-one advanced drug delivery system …

Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

The immune microenvironment plays a vital role in bone defect repair. To create an immune
microenvironment that promotes osteogenesis, researchers are exploring ways to enhance …

Paraquat (PQ) is the most widely used herbicide in the world and a well-known potent
neurotoxin for humans. PQ exposure has been linked to increase the risk of Parkinson's …