Precision medicine advances in idiopathic pulmonary fibrosis

T Karampitsakos, BM Juan-Guardela, A Tzouvelekis… - …, 2023 - thelancet.com
Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous, unpredictable and ultimately
lethal chronic lung disease. Over the last decade, two anti-fibrotic agents have been shown …

Genetics and genomics of pulmonary fibrosis: charting the molecular landscape and sha** precision medicine

A Adegunsoye, JA Kropski, J Behr… - American Journal of …, 2024 - atsjournals.org
Recent genetic and genomic advancements have elucidated the complex etiology of
idiopathic pulmonary fibrosis (IPF) and other progressive fibrotic interstitial lung diseases …

The role of inflammation and fibrosis in interstitial lung disease treatment decisions

J Behr, ML Salisbury, SLF Walsh… - American Journal of …, 2024 - atsjournals.org
Interstitial lung disease (ILD) is a large and heterogeneous group of diseases manifesting
primarily in the distal bronchoalveolar space. Some ILDs have identifiable causes or …

Machine learning of plasma proteomics classifies diagnosis of interstitial lung disease

Y Huang, SF Ma, JM Oldham… - American Journal of …, 2024 - atsjournals.org
Rationale: Distinguishing connective tissue disease–associated interstitial lung disease
(CTD-ILD) from idiopathic pulmonary fibrosis (IPF) can be clinically challenging. Objectives …

Contemporary concise review 2023: interstitial lung disease

Y Moodley - Respirology, 2024 - Wiley Online Library
SUMMARY OF KEY POINTS In this review, we have discussed several important
developments in 2023 in Interstitial Lung Disease (ILD). The association of pollution with …

Transbronchial lung cryobiopsy performed with cone beam computed tomography guidance versus fluoroscopy: a retrospective cohort review

SO Ali, C Castellani, BS Benn - Lung, 2024 - Springer
Purpose Determining the cause of interstitial lung disease (ILD) remains challenging. While
surgical lung biopsy remains the gold standard approach, risks associated with it may be …

Spatially resolved gene expression profiles of fibrosing interstitial lung diseases

SJ Kim, MJ Cecchini, E Woo, N Jayawardena… - Scientific Reports, 2024 - nature.com
Fibrosing interstitial lung diseases (ILDs) encompass a diverse range of scarring disorders
that lead to progressive lung failure. Previous gene expression profiling studies focused on …

[HTML][HTML] Employment of the Envisia genomic classifier in conjunction with cryobiopsy in patients with undiagnosed interstitial lung disease

F Kheir, R Abdelghani, D Espinoza, R Villalobos… - Chest Pulmonary, 2024 - Elsevier
Background The Envisia Genomic Classifier (EGC) is a clinically validated molecular
diagnostic test identifying usual interstitial pneumonia (UIP), increasing the diagnostic …

Development and Validation of a Clinical, CT, Genomic Classifier and BAL Scoring System for Diagnosing IPF

MLW Kam, ELH Tjong, S Chaudhary… - European …, 2025 - publications.ersnet.org
The utility of incorporating a usual interstitial pneumonia (UIP) genomic classifier (GC) and
bronchoalveolar lavage (BAL) cell count analysis alongside traditional clinical-imaging …

Interstitial Pneumonia with Autoimmune Features: 8 Years after Nomenclature and Classification—Where are We Not and Where Are We Headed?

T Kulkarni - Current Pulmonology Reports, 2023 - Springer
Abstract Purpose of Review The term interstitial pneumonia with autoimmune features
(IPAF) was proposed by an international task force as a research classification to …