Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their potent
antibacterial and wound healing properties. Bare AMPs have limited activity following topical …

As one of the first defenders of innate immune response, neutrophils make a rapid and
robust response against infection or harmful agents. While traditionally regarded as suicidal …

Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …

Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …

Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …

Antimicrobial peptides (AMPs), especially antibacterial peptides, have been widely
investigated as potential alternatives to antibiotic-based therapies. Indeed, naturally …