Lab under the skin: microneedle based wearable devices

H Teymourian, F Tehrani, K Mahato… - Advanced healthcare …, 2021 - Wiley Online Library
While the current smartwatches and cellphones can readily track mobility and vital signs, a
new generation of wearable devices is rapidly develo** to enable users to monitor their …

An overview of microneedle applications, materials, and fabrication methods

ZF Rad, PD Prewett, GJ Davies - Beilstein journal of …, 2021 - beilstein-journals.org
Microneedle-based microdevices promise to expand the scope for delivery of vaccines and
therapeutic agents through the skin and withdrawing biofluids for point-of-care diagnostics …

[HTML][HTML] Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development

E Larrañeta, REM Lutton, AD Woolfson… - Materials Science and …, 2016 - Elsevier
Transdermal drug delivery offers a number of advantages for the patient, due not only its non-
invasive and convenient nature, but also factors such as avoidance of first pass metabolism …

Microneedles for drug and vaccine delivery

YC Kim, JH Park, MR Prausnitz - Advanced drug delivery reviews, 2012 - Elsevier
Microneedles were first conceptualized for drug delivery many decades ago, but only
became the subject of significant research starting in the mid-1990's when microfabrication …

[HTML][HTML] Recent advancements in microneedle technology for multifaceted biomedical applications

D Kulkarni, F Damiri, S Rojekar, M Zehravi… - Pharmaceutics, 2022 - mdpi.com
Microneedle (MNs) technology is a recent advancement in biomedical science across the
globe. The current limitations of drug delivery, like poor absorption, low bioavailability …

Microneedle technologies for (trans) dermal drug and vaccine delivery

K Van Der Maaden, W Jiskoot, J Bouwstra - Journal of controlled release, 2012 - Elsevier
Microneedles have been used for the dermal and transdermal delivery of a broad range of
drugs, such as small molecular weight drugs, oligonucleotides, DNA, peptides, proteins and …

[HTML][HTML] Hollow microneedles for ocular drug delivery

S Gade, K Glover, D Mishra, S Sharma, O Guy… - Journal of Controlled …, 2024 - Elsevier
Microneedles (MNs) are micron-sized needles, typically< 2 mm in length, arranged either as
an array or as single needle. These MNs offer a minimally invasive approach to ocular drug …

Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety

RF Donnelly, TRR Singh, AD Woolfson - Drug delivery, 2010 - Taylor & Francis
Many promising therapeutic agents are limited by their inability to reach the systemic
circulation, due to the excellent barrier properties of biological membranes, such as the …

Super-short solid silicon microneedles for transdermal drug delivery applications

L Wei-Ze, H Mei-Rong, Z Jian-**… - International journal of …, 2010 - Elsevier
In this study, the super-short microneedles with a length of 70–80μm were fabricated using
silicon wet etching technology. As evident from the visual inspection of pierced human skin …

Drawing lithography for microneedles: a review of fundamentals and biomedical applications

K Lee, H Jung - Biomaterials, 2012 - Elsevier
A microneedle is a three-dimensional (3D) micromechanical structure and has been in the
spotlight recently as a drug delivery system (DDS). Because a microneedle delivers the …