MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Batch effects in MALDI mass spectrometry imaging

B Balluff, C Hopf, T Porta Siegel… - Journal of the …, 2021 - ACS Publications
Mass spectrometry imaging (MSI) has become an indispensible tool for spatially resolved
molecular investigation of tissues. One of the key application areas is biomedical research …

Cardinal v. 3: a versatile open-source software for mass spectrometry imaging analysis

KA Bemis, MC Föll, D Guo, SS Lakkimsetty, O Vitek - Nature Methods, 2023 - nature.com
Cardinal v. 3 is an open-source software for reproducible analysis of mass spectrometry
imaging experiments. A major update from its previous versions, Cardinal v. 3 supports most …

Advancing rare cancer research by MALDI mass spectrometry imaging: Applications, challenges, and future perspectives in sarcoma

MN Stillger, MJ Li, P Hönscheid, C von Neubeck… - …, 2024 - Wiley Online Library
MALDI mass spectrometry imaging (MALDI imaging) uniquely advances cancer research, by
measuring spatial distribution of endogenous and exogenous molecules directly from tissue …

Colocalization features for classification of tumors using desorption electrospray ionization mass spectrometry imaging

P Inglese, G Correia, P Pruski, RC Glen… - Analytical …, 2019 - ACS Publications
Supervised modeling of mass spectrometry imaging (MSI) data is a crucial component for
the detection of the distinct molecular characteristics of cancerous tissues. Currently, two …

[HTML][HTML] Metabolite Profiling of Hydroponic Lettuce Roots Affected by Nutrient Solution Flow: Insights from Comprehensive Analysis Using Widely Targeted …

B Baiyin, Y **ang, Y Shao, JE Son, K Tagawa… - International Journal of …, 2024 - mdpi.com
Root morphology, an important determinant of nutrient absorption and plant growth, can
adapt to various growth environments to promote survival. Solution flow under hydroponic …

Unsupervised segmentation of mass spectrometric ion images characterizes morphology of tissues

D Guo, K Bemis, C Rawlins, J Agar, O Vitek - Bioinformatics, 2019 - academic.oup.com
Motivation Mass spectrometry imaging (MSI) characterizes the spatial distribution of ions in
complex biological samples such as tissues. Since many tissues have complex morphology …

Characterization of spatial heterogeneity in metastasized colorectal cancer by MALDI Imaging

L Moritz, MN Stillger, F Takács, H Füllgraf, M Werner… - 2023 - preprints.org
About 50% of colorectal cancer patients develop liver metastases. Patients with metastatic
colorectal cancer have 5-year survival rates below 20% despite new therapeutic regimens …

MALDI Mass Spectrometry Imaging of Neuropeptides

J Hanrieder - 2021 - books.rsc.org
Neuropeptides, including peptide hormones, are key modulators in the brain that represent
the largest class of chemical messengers for cell-to-cell communication. 1–5 Due to the …

The Role of Informatics and Data Analysis in MALDI Mass Spectrometry Imaging

B Balluff - 2021 - books.rsc.org
Mass spectrometry imaging (MSI), and especially matrix-assisted laser desorption/ionization
(MALDI), has become an integral part of biochemical sciences. Particularly biomedical …