Identification and evaluation of anti-inflammatory properties of aqueous components extracted from sesame (Sesamum indicum) oil

P Deme, CA Narasimhulu, S Parthasarathy - Journal of chromatography B, 2018 - Elsevier
We previously reported that sesame oil (SO) has anti-inflammatory, anti-atherosclerotic and
lipid lowering properties in vivo. Our recent studies have shown that, an aqueous extract of …

Primary prevention of atherosclerosis by pretreatment of low-density lipoprotein receptor knockout mice with sesame oil and its aqueous components

C Aluganti Narasimhulu, KY Burge, M Doomra… - Scientific Reports, 2018 - nature.com
Pharmacological intervention using statins and PCSK9 inhibitors have become first-line
therapy in the prevention of hypercholesterolemia and atherosclerosis. Currently, no agent …

Alzheimer's disease markers in aged ApoE-PON1 deficient mice

C Aluganti Narasimhulu, C Mitra… - Journal of …, 2019 - content.iospress.com
Background: Alzheimer's disease (AD) is a neurodegenerative disorder associated with
aging. Cardiovascular risk factors like hypertension and atherosclerosis increase the risk for …

Sesame oil and an aqueous extract derived from sesame oil enhance regression of preexisting atherosclerotic lesions in low-density lipoprotein receptor knockout …

CA Narasimhulu, A Riad… - Journal of medicinal …, 2018 - liebertpub.com
Diet and exercise are recommended both as a prophylactic and as a therapeutic approach
for patients with established coronary artery disease. We previously reported that sesame oil …

A novel mechanism for atherosclerotic calcification: potential resolution of the oxidation paradox

A Riad, CA Narasimhulu, P Deme… - Antioxidants & redox …, 2018 - liebertpub.com
Aim: In this study, we tested the hypothesis that lipid peroxide-derived dicarboxylic acids
(DCAs), by virtue of their ability to bind to calcium (Ca), might be involved in atherosclerotic …