Infectious disease (ID) is one of the top-most serious threats to human health globally,
further aggravated by antimicrobial resistance and lack of novel immunization options …

The task of predicting the interactions between drugs and targets plays a key role in the
process of drug discovery. There is a need to develop novel and efficient prediction …

The COVID-19 pandemic has highlighted the need to quickly and reliably prioritize clinically
approved compounds for their potential effectiveness for severe acute respiratory syndrome …

Drug combinations, offering increased therapeutic efficacy and reduced toxicity, play an
important role in treating multiple complex diseases. Yet, our ability to identify and validate …

Drug discovery and development affects various aspects of human health and dramatically
impacts the pharmaceutical market. However, investments in a new drug often go …

The identification of interactions between drugs/compounds and their targets is crucial for
the development of new drugs. In vitro screening experiments (ie bioassays) are frequently …

Drug interactions, including drug–drug interactions (DDIs) and drug–food constituent
interactions (DFIs), can trigger unexpected pharmacological effects, including adverse drug …

New drug discovery has been acknowledged as a complicated, expensive, time-consuming,
and challenging project. It has been estimated that around 12 years and 2.7 billion USD, on …

Here we identify hundreds of new drug-disease associations for over 900 FDA-approved
drugs by quantifying the network proximity of disease genes and drug targets in the human …

The process for drug discovery and development is challenging, time consuming and
expensive. Computer-aided drug discovery (CADD) tools can act as a virtual shortcut …