Dystrophin-and utrophin-based therapeutic approaches for treatment of duchenne muscular dystrophy: a comparative review
Duchenne muscular dystrophy is a devastating disease that leads to progressive muscle
loss and premature death. While medical management focuses mostly on symptomatic …
loss and premature death. While medical management focuses mostly on symptomatic …
Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles
K Swiderski, T Naim, J Trieu, A Chee… - Physiological …, 2024 - Wiley Online Library
The dystrophin protein has well‐characterized roles in force transmission and maintaining
membrane integrity during muscle contraction. Studies have reported decreased expression …
membrane integrity during muscle contraction. Studies have reported decreased expression …
[HTML][HTML] Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia
K Swiderski, J Trieu, A Chee, T Naim, CJ Brock… - Life Sciences, 2025 - Elsevier
Aims Cancer cachexia affects up to 80% of patients with advanced cancer and accounts for>
20% of all cancer-related deaths. Sarcolemmal localization of dystrophin, a key protein …
20% of all cancer-related deaths. Sarcolemmal localization of dystrophin, a key protein …
Two operational modes of atomic force microscopy reveal similar mechanical properties for homologous regions of dystrophin and utrophin
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by the absence of
the protein dystrophin. Dystrophin is hypothesized to work as a molecular shock absorber …
the protein dystrophin. Dystrophin is hypothesized to work as a molecular shock absorber …
Identifying single molecule force spectroscopy data using deep learning with physics augmentation
C Hua - openreview.net
Deciphering the pathways of protein folding and unfolding under tension is essential for
deepening our understanding of fundamental biological mechanisms. Such insights offer the …
deepening our understanding of fundamental biological mechanisms. Such insights offer the …