Natural products as anticancer agents: current status and future perspectives
A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …
years. Several compounds have been synthesized from natural products by modifying their …
Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …
Natural products/bioactive compounds as a source of anticancer drugs
Simple Summary Cancer is considered as a large group of diseases involving abnormal cell
growth, which results in an alarming rise in the mortality rate at the worldwide level …
growth, which results in an alarming rise in the mortality rate at the worldwide level …
Anticancer applications and pharmacological properties of piperidine and piperine: a comprehensive review on molecular mechanisms and therapeutic perspectives
S Mitra, U Anand, NK Jha, MS Shekhawat… - Frontiers in …, 2022 - frontiersin.org
Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …
Piperidine nucleus in the field of drug discovery
Background Piperidine is an essential heterocyclic system and a pivotal cornerstone in the
production of drugs. Piperidine byproducts showed several important pharmacophoric …
production of drugs. Piperidine byproducts showed several important pharmacophoric …
Role of plant-derived active constituents in cancer treatment and their mechanisms of action
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …
one of the main causes of death worldwide. Although substantial progress has been made …
Mechanisms of action of fruit and vegetable phytochemicals in colorectal cancer prevention
Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is
expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly …
expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly …
Piperine: an emerging biofactor with anticancer efficacy and therapeutic potential
Anticancer drug discovery needs serious attention to overcome the high mortality rate
caused by cancer. There are still many obstacles to treating this disease, such as the high …
caused by cancer. There are still many obstacles to treating this disease, such as the high …
The promise of Piperine in cancer chemoprevention
Simple Summary With 19.3 million new cancer cases worldwide and nearly 10.0 million
cancer-related deaths cancer is a global health challenge. Cancer is a disease caused by a …
cancer-related deaths cancer is a global health challenge. Cancer is a disease caused by a …
Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks
an actionable target with limited treatment options beyond conventional chemotherapy …
an actionable target with limited treatment options beyond conventional chemotherapy …