Evolution of genetic networks for human creativity

I Zwir, C Del-Val, M Hintsanen, KM Cloninger… - Molecular …, 2022‏ - nature.com
The genetic basis for the emergence of creativity in modern humans remains a mystery
despite sequencing the genomes of chimpanzees and Neanderthals, our closest hominid …

Single cell transcriptional signatures of the human placenta in term and preterm parturition

R Pique-Regi, R Romero, AL Tarca, ED Sendler, Y Xu… - Elife, 2019‏ - elifesciences.org
More than 135 million births occur each year; yet, the molecular underpinnings of human
parturition in gestational tissues, and in particular the placenta, are still poorly understood …

Three genetic–environmental networks for human personality

I Zwir, C Del-Val, J Arnedo, L Pulkki-Råback… - Molecular …, 2021‏ - nature.com
Phylogenetic, developmental, and brain-imaging studies suggest that human personality is
the integrated expression of three major systems of learning and memory that regulate (1) …

Natural disaster and immunological aging in a nonhuman primate

MM Watowich, KL Chiou, MJ Montague… - Proceedings of the …, 2022‏ - pnas.org
Weather-related disasters are increasing in frequency and severity, leaving survivors to
cope with ensuing mental, financial, and physical hardships. This adversity can exacerbate …

Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions

AS Findley, A Monziani, AL Richards, K Rhodes… - Elife, 2021‏ - elifesciences.org
Genetic effects on gene expression and splicing can be modulated by cellular and
environmental factors; yet interactions between genotypes, cell type, and treatment have not …

[HTML][HTML] Increasing diversity of functional genetics studies to advance biological discovery and human health

SHL George, A Medina-Rivera, Y Idaghdour… - The American Journal of …, 2023‏ - cell.com
In this perspective we discuss the current lack of genetic and environmental diversity in
functional genomics datasets. There is a well-described Eurocentric bias in genetic and …

Evolutionary divergence between homologous X–Y chromosome genes shapes sex-biased biology

AR DeCasien, K Tsai, S Liu, A Thomas… - Nature Ecology & …, 2025‏ - nature.com
Sex chromosomes are a fundamental aspect of sex-biased biology, but the extent to which
homologous X–Y gene pairs ('the gametologs') contribute to sex-biased phenotypes …

Genotype by environment interaction for gene expression in Drosophila melanogaster

W Huang, MA Carbone, RF Lyman, RRH Anholt… - Nature …, 2020‏ - nature.com
The genetics of phenotypic responses to changing environments remains elusive. Using
whole-genome quantitative gene expression as a model, here we study how the genetic …

[HTML][HTML] Isolation disrupts social interactions and destabilizes brain development in bumblebees

ZY Wang, GC McKenzie-Smith, W Liu, HJ Cho… - Current Biology, 2022‏ - cell.com
Social isolation, particularly in early life, leads to deleterious physiological and behavioral
outcomes. Here, we leverage new high-throughput tools to comprehensively investigate the …

Characterizing the landscape of gene expression variance in humans

S Wolf, D Melo, KM Garske, LF Pallares, AJ Lea… - PLoS …, 2023‏ - journals.plos.org
Gene expression variance has been linked to organismal function and fitness but remains a
commonly neglected aspect of molecular research. As a result, we lack a comprehensive …