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[HTML][HTML] Empowering biomedical discovery with AI agents
We envision" AI scientists" as systems capable of skeptical learning and reasoning that
empower biomedical research through collaborative agents that integrate AI models and …
empower biomedical research through collaborative agents that integrate AI models and …
[HTML][HTML] How to build the virtual cell with artificial intelligence: Priorities and opportunities
Cells are essential to understanding health and disease, yet traditional models fall short of
modeling and simulating their function and behavior. Advances in AI and omics offer …
modeling and simulating their function and behavior. Advances in AI and omics offer …
Establishing a conceptual framework for holistic cell states and state transitions
SM Rafelski, JA Theriot - Cell, 2024 - cell.com
Cell states were traditionally defined by how they looked, where they were located, and what
functions they performed. In this post-genomic era, the field is largely focused on a …
functions they performed. In this post-genomic era, the field is largely focused on a …
Opportunities and challenges for deep learning in cell dynamics research
The growth of artificial intelligence (AI) has led to an increase in the adoption of computer
vision and deep learning (DL) techniques for the evaluation of microscopy images and …
vision and deep learning (DL) techniques for the evaluation of microscopy images and …
Spatial modeling algorithms for reactions and transport in biological cells
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to
control their functions. Such cell signaling networks have been a common focus for …
control their functions. Such cell signaling networks have been a common focus for …
Toward generalizable phenotype prediction from single-cell morphology representations
Functional cell processes (eg, molecular signaling, response to stimuli, mitosis, etc.) impact
cell phenotypes, which scientists can measure with cell morphology. However, linking these …
cell phenotypes, which scientists can measure with cell morphology. However, linking these …
Spatial modeling algorithms for reactions and transport (SMART) in biological cells
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to
control their many functions. Such cell signaling networks have been a common focus for …
control their many functions. Such cell signaling networks have been a common focus for …
AI: A transformative opportunity in cell biology
The success of artificial intelligence (AI) algorithms in predicting protein structure and more
recently, protein interactions, demonstrates the power and potential of machine learning and …
recently, protein interactions, demonstrates the power and potential of machine learning and …
A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
Organ function requires coordinated activities of thousands of genes in distinct, spatially
organized cell types. Understanding the basis of emergent tissue function requires …
organized cell types. Understanding the basis of emergent tissue function requires …
CellFlow: Simulating Cellular Morphology Changes via Flow Matching
Building a virtual cell capable of accurately simulating cellular behaviors in silico has long
been a dream in computational biology. We introduce CellFlow, an image-generative model …
been a dream in computational biology. We introduce CellFlow, an image-generative model …