Sample preparation method

DJ Turner, CG Brown, SW Reid, JA Clarke… - US Patent …, 2017 - Google Patents
References Cited(57) US PATENT DOCUMENTS The invention relates to a method for
modifying a template polynucleotide for characterization, especially for nanopore 6.426. 231 …

Modified nanopores, compositions comprising the same, and uses thereof

G Maglia, L Franceschini, T Brouns, AJ Heron… - US Patent …, 2021 - Google Patents
6,927,070 B1 7,189,503 B2 8,105,846 B2 8,785,211 B2 8,822,160 B2 8,828,208 B2
9,073,990 B2* 9,127,313 B2 9,222,082 B2 9,447,152 B2 9,562,887 B2 9,580,480 B2 …

Mutant lysenin pores

M Bruce, JA Clarke, AJ Heron, L Jayasinghe… - US Patent …, 2021 - Google Patents
US10882889B2 - Mutant lysenin pores - Google Patents US10882889B2 - Mutant lysenin
pores - Google Patents Mutant lysenin pores Download PDF Info Publication number …

Method for sequencing a heteropolymeric target nucleic acid sequence

DJ Stoddart, AJ Heron, G Maglia… - US Patent 10,669,581, 2020 - Google Patents
The invention relates to a method for sequencing a heteropolymeric target nucleic acid
sequence that involves stochastic sensing. The invention also relates to a method for …

Nanopore biosensors for detection of proteins and nucleic acids

G Maglia, M Soskine - US Patent 10,514,378, 2019 - Google Patents
5,817,771 A 5,985,834 A 6,015,714 A 6,114,121 A 6,123,819 A 6,127,166 A 6,251,610 B1
6,362,002 B1 6,426,231 B1 6,451,563 B1 6,627,067 B1 6,824,659 B2 6,863,833 B1 …

Mutant pore

L Jayasinghe, EJ Wallace - US Patent 10,975,428, 2021 - Google Patents
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …

Mutant pore

L Jayasinghe, EJ Wallace - US Patent 11,186,868, 2021 - Google Patents
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …

Mutant pores

L Jayasinghe, EJ Wallace - US Patent 10,995,372, 2021 - Google Patents
US10995372B2 - Mutant pores - Google Patents US10995372B2 - Mutant pores - Google
Patents Mutant pores Download PDF Info Publication number US10995372B2 …

Mutant pores

S Howorka, H Remaut, L Jayasinghe… - US Patent …, 2021 - Google Patents
US11034734B2 - Mutant pores - Google Patents US11034734B2 - Mutant pores - Google
Patents Mutant pores Download PDF Info Publication number US11034734B2 US11034734B2 …

Nanopores with internal protein adaptors

G Maglia, M Soskine, A Biesemans… - US Patent …, 2021 - Google Patents
A method for detecting an analyte in a sample includes the steps of obtaining a nanopore
sensor comprising a nanopore and a protein adaptor internalized in the lumen of the …