Review and consensus recommendations on clinical APT‐weighted imaging approaches at 3T: application to brain tumors

J Zhou, M Zaiss, L Knutsson, PZ Sun… - Magnetic resonance …, 2022 - Wiley Online Library
Amide proton transfer‐weighted (APTw) MR imaging shows promise as a biomarker of brain
tumor status. Currently used APTw MRI pulse sequences and protocols vary substantially …

Advanced imaging techniques for neuro-oncologic tumor diagnosis, with an emphasis on PET-MRI imaging of malignant brain tumors

WB Overcast, KM Davis, CY Ho, GD Hutchins… - Current Oncology …, 2021 - Springer
Abstract Purpose of Review This review will explore the latest in advanced imaging
techniques, with a focus on the complementary nature of multiparametric, multimodality …

MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond

B Vachha, SY Huang - European Radiology Experimental, 2021 - Springer
Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient
technology has provided enormous gains in sensitivity, resolution, and contrast for …

Quantitative imaging of apoptosis following oncolytic virotherapy by magnetic resonance fingerprinting aided by deep learning

O Perlman, H Ito, K Herz, N Shono… - Nature biomedical …, 2022 - nature.com
Non-invasive imaging methods for detecting intratumoural viral spread and host responses
to oncolytic virotherapy are either slow, lack specificity or require the use of radioactive or …

7 Tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging

T Platt, ME Ladd, D Paech - Investigative radiology, 2021 - journals.lww.com
Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Assessment and prediction of glioblastoma therapy response: challenges and opportunities

D Qi, J Li, CC Quarles, E Fonkem, E Wu - Brain, 2023 - academic.oup.com
Glioblastoma is the most aggressive type of primary adult brain tumour. The median survival
of patients with glioblastoma remains approximately 15 months, and the 5-year survival rate …

Relaxation-compensated amide proton transfer (APT) MRI signal intensity is associated with survival and progression in high-grade glioma patients

D Paech, C Dreher, S Regnery, JE Meissner… - European …, 2019 - Springer
Objectives The purpose of this study was to investigate the association of relaxation-
compensated chemical exchange saturation transfer (CEST) MRI with overall survival (OS) …

Evolving concepts in margin strategies and adaptive radiotherapy for glioblastoma: A new future is on the horizon

CL Tseng, KL Zeng, EA Mellon, SG Soltys… - Neuro …, 2024 - academic.oup.com
Chemoradiotherapy is the standard treatment after maximal safe resection for glioblastoma
(GBM). Despite advances in molecular profiling, surgical techniques, and neuro-imaging …

Early response assessment of glioma patients to definitive chemoradiotherapy using chemical exchange saturation transfer imaging at 7 T

JE Meissner, A Korzowski, S Regnery… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Patients with newly diagnosed inoperable glioma receive chemoradiotherapy
(CRT). Standard Response Assessment in Neuro‐Oncology (RANO) takes a minimum of 4 …

Reproducibility of APT-weighted CEST-MRI at 3T in healthy brain and tumor across sessions and scanners

Y Wu, TC Wood, SHAE Derks, IJ Pruis… - Scientific reports, 2023 - nature.com
Amide proton transfer (APT)-weighted chemical exchange saturation transfer (CEST)
imaging is a recent MRI technique making its way into clinical application. In this work, we …