Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section

E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

B12-dependent photoresponsive protein hydrogels for controlled stem cell/protein release

R Wang, Z Yang, J Luo, IM Hsing… - Proceedings of the …, 2017 - National Acad Sciences
Thanks to the precise control over their structural and functional properties, genetically
engineered protein-based hydrogels have emerged as a promising candidate for …

Structural basis for gene regulation by a B12-dependent photoreceptor

M Jost, J Fernández-Zapata, MC Polanco… - Nature, 2015 - nature.com
Photoreceptor proteins enable organisms to sense and respond to light. The newly
discovered CarH-type photoreceptors use a vitamin B12 derivative, adenosylcobalamin, as …

Insights into the lifestyle of uncultured bacterial natural product factories associated with marine sponges

G Lackner, EE Peters… - Proceedings of the …, 2017 - National Acad Sciences
The as-yet uncultured filamentous bacteria “Candidatus Entotheonella factor” and
“Candidatus Entotheonella gemina” live associated with the marine sponge Theonella …

Injectable, photoresponsive hydrogels for delivering neuroprotective proteins enabled by metal-directed protein assembly

B Jiang, X Liu, C Yang, Z Yang, J Luo, S Kou, K Liu… - Science …, 2020 - science.org
Axon regeneration constitutes a fundamental challenge for regenerative neurobiology,
which necessitates the use of tailor-made biomaterials for controllable delivery of cells and …

Vitamin B12 in the spotlight again

J Bridwell-Rabb, CL Drennan - Current opinion in chemical biology, 2017 - Elsevier
Highlights•Adenosylcobalamin repurposed for light-dependent gene regulation.•Methylation
of mercury may require transfer of a methyl anion from methylcobalamin.•A third class of …

Green‐light‐induced inactivation of receptor signaling using cobalamin‐binding domains

S Kainrath, M Stadler, E Reichhart… - Angewandte Chemie …, 2017 - Wiley Online Library
Optogenetics and photopharmacology provide spatiotemporally precise control over protein
interactions and protein function in cells and animals. Optogenetic methods that are …

A New Facet of Vitamin B12: Gene Regulation by Cobalamin-Based Photoreceptors

S Padmanabhan, M Jost, CL Drennan… - Annual review of …, 2017 - annualreviews.org
Living organisms sense and respond to light, a crucial environmental factor, using
photoreceptors, which rely on bound chromophores such as retinal, flavins, or linear …

Dynamically tunable light responsive silk-elastin-like proteins

OP Narayan, X Mu, O Hasturk, DL Kaplan - Acta biomaterialia, 2021 - Elsevier
Dynamically tunable biomaterials are of particular interest in the field of biomedical
engineering because of the potential utility for shape-change materials, drug and cell …