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Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin
RE Veerman, L Teeuwen, P Czarnewski… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are increasingly tested as therapeutic vehicles and biomarkers,
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …
but still EV subtypes are not fully characterised. To isolate EVs with few co‐isolated entities …
Clinical delivery of circular RNA: lessons learned from RNA drug development
Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …
which play diverse roles in regulating biological processes and disease states. The …
Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small …
Small extracellular vesicles (sEVs) provide major promise for advances in cancer
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
Advances and utility of the human plasma proteome
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
stratify, or possibly prevent diseases. With recent technological advances and the urgent …
Beyond extracellular vesicles: hybrid membrane nanovesicles as emerging advanced tools for biomedical applications
M Sun, J Yang, Y Fan, Y Zhang, J Sun, M Hu… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs), involved in essential physiological and pathological processes
of the organism, have emerged as powerful tools for disease treatment owing to their unique …
of the organism, have emerged as powerful tools for disease treatment owing to their unique …
Adhesive hydrogels in osteoarthritis: from design to application
WL Duan, LN Zhang, R Bohara… - Military Medical …, 2023 - Springer
Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …
of the global population and more than 500 million people worldwide. One research frontier …
Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma
H Luo, H Zhang, J Mao, H Cao, Y Tao, G Zhao… - Cell Death & …, 2023 - nature.com
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: A decade of research
Prostate cancer is a global cancer burden and considerable effort has been made through
the years to identify biomarkers for the disease. Approximately a decade ago, the potential of …
the years to identify biomarkers for the disease. Approximately a decade ago, the potential of …