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Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
The physical and biochemical properties of the extracellular matrix regulate cell fate
The extracellular matrix is a complex network of hydrated macromolecular proteins and
sugars that, in concert with bound soluble factors, comprise the acellular stromal …
sugars that, in concert with bound soluble factors, comprise the acellular stromal …
Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D
We report the first investigation into the bioprinting of human induced pluripotent stem cells
(hiPSCs), their response to a valve-based printing process as well as their post-printing …
(hiPSCs), their response to a valve-based printing process as well as their post-printing …
Natural polymers for the microencapsulation of cells
The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an
attractive procedure for many biomedical and biotechnological applications, such as …
attractive procedure for many biomedical and biotechnological applications, such as …
3D neural tissue models: From spheroids to bioprinting
Abstract Three-dimensional (3D) in vitro neural tissue models provide a better recapitulation
of in vivo cell-cell and cell-extracellular matrix interactions than conventional two …
of in vivo cell-cell and cell-extracellular matrix interactions than conventional two …
Design and printing strategies in 3D bioprinting of cell‐hydrogels: A review
Bioprinting is an emerging technology that allows the assembling of both living and non‐
living biological materials into an ideal complex layout for further tissue maturation …
living biological materials into an ideal complex layout for further tissue maturation …
Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …
decade. Their multilineage differentiation potentials and immunomodulatory properties have …
Present and future of tissue engineering scaffolds for dentin‐pulp complex regeneration
More than two thirds of the global population suffers from tooth decay, which results in
cavities with various levels of lesion severity. Clinical interventions to treat tooth decay range …
cavities with various levels of lesion severity. Clinical interventions to treat tooth decay range …
Spatially and temporally controlled hydrogels for tissue engineering
Recent years have seen tremendous advances in the field of hydrogel-based biomaterials.
One of the most prominent revolutions in this field has been the integration of elements or …
One of the most prominent revolutions in this field has been the integration of elements or …
A smart aminoglycoside hydrogel with tunable gel degradation, on-demand drug release, and high antibacterial activity
Aminoglycosides are a family of critically important antibiotics for the treatment of serious
infections including multidrug-resistant pathogens. However, clinical use of aminoglycoside …
infections including multidrug-resistant pathogens. However, clinical use of aminoglycoside …