A full understanding of Parkinson's Disease etiopathogenesis and of the causes of the
preferential vulnerability of nigrostriatal dopaminergic neurons is still an unsolved puzzle. A …

Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

The EcoCyc model-organism database collects and summarizes experimental data for
Escherichia coli K-12. EcoCyc is regularly updated by the manual curation of individual …

Enolase 1 (ENO1) is a moonlighting protein, function as a glycolysis enzyme, a plasminogen
receptor and a DNA binding protein. ENO1 play an important role in the process of cancer …

Acetylation is a posttranslational modification conserved in all domains of life that is carried
out by N-acetyltransferases. While acetylation can occur on N α-amino groups, this review …

Protein acetylation is a reversible post-translational modification, and is involved in many
biological processes in cells, such as transcriptional regulation, DNA damage repair, and …

Posttranslational modification of a protein, either alone or in combination with other
modifications, can control properties of that protein, such as enzymatic activity, localization …

Lysine acetylation (Kac), an abundant post-translational modification (PTM) in prokaryotes,
regulates various microbial metabolic pathways. However, no studies have examined …

Histone deacetylases (HDACs) are zinc-dependent deacetylases that remove acetyl groups
from lysine residues of histones or form protein complexes with other proteins for …

Protein acetylation is an evolutionarily conserved posttranslational modification. It affects
enzyme activity, metabolic flux distribution, and other critical physiological and biochemical …