Neuroinflammation in bipolar depression

F Benedetti, V Aggio, ML Pratesi, G Greco… - Frontiers in …, 2020 - frontiersin.org
Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …

Inflamed moods: a review of the interactions between inflammation and mood disorders

JD Rosenblat, DS Cha, RB Mansur… - Progress in Neuro …, 2014 - Elsevier
Mood disorders have been recognized by the World Health Organization (WHO) as the
leading cause of disability worldwide. Notwithstanding the established efficacy of …

Bipolar disorder and immune dysfunction: epidemiological findings, proposed pathophysiology and clinical implications

JD Rosenblat, RS McIntyre - Brain sciences, 2017 - mdpi.com
Bipolar disorder (BD) is strongly associated with immune dysfunction. Replicated
epidemiological studies have demonstrated that BD has high rates of inflammatory medical …

An overview of links between obesity and mental health

C Avila, AC Holloway, MK Hahn, KM Morrison… - Current obesity …, 2015 - Springer
Abstract The American Medical Association recently recognized obesity as both an illness
and a leading cause of preventable death and chronic disease. This association is not only …

Cytokine alterations in bipolar disorder: a meta-analysis of 30 studies

A Modabbernia, S Taslimi, E Brietzke, M Ashrafi - Biological psychiatry, 2013 - Elsevier
BACKGROUND: We conducted a meta-analysis of studies comparing cytokine
concentrations between patients with bipolar disorder (BD) and healthy control subjects …

Treatment-resistant depression: definitions, review of the evidence, and algorithmic approach

RS McIntyre, MJ Filteau, L Martin, S Patry… - Journal of affective …, 2014 - Elsevier
Background Most adults with major depressive disorder (MDD) fail to achieve remission with
index pharmacological treatment. Moreover, at least half will not achieve and sustain …

[HTML][HTML] Role of microglia in CNS inflammation

MB Graeber, W Li, ML Rodriguez - FEBS letters, 2011 - Elsevier
There is increasing confusion about the meaning of the terms inflammation,
neuroinflammation, and microglial inflammation. We aim in this review to achieve greater …

Obesity and psychiatric disorders: commonalities in dysregulated biological pathways and their implications for treatment

AL Lopresti, PD Drummond - Progress in Neuro-Psychopharmacology and …, 2013 - Elsevier
Rates of obesity are higher than normal across a range of psychiatric disorders, including
major depressive disorder, bipolar disorder, schizophrenia and anxiety disorders. While the …

A review of the psychosocial aspects of clinically severe obesity and bariatric surgery.

DB Sarwer, LJ Heinberg - American Psychologist, 2020 - psycnet.apa.org
For the past 2 decades, clinically severe obesity (operationalized as a body mass index≥
40 kg/m 2) has increased at a more pronounced rate that less severe obesity. As a result, the …

In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS …

M Maes, M Kubera, JC Leunis, M Berk… - Acta psychiatrica …, 2013 - Wiley Online Library
Maes M, Kubera M, Leunis J‐C, Berk M, Geffard M, Bosmans E. In depression, bacterial
translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS) …