Biocompatibility, biodegradation and biomedical applications of poly (lactic acid)/poly (lactic-co-glycolic acid) micro and nanoparticles

EM Elmowafy, M Tiboni, ME Soliman - Journal of Pharmaceutical …, 2019 - Springer
Background Poly (lactic acid)(PLA) and poly (lactic-co-glycolic acid)(PLGA) are among the
well-documented FDA-approved polymers used for the preparation of safe and effective …

Recent advances in bioplastics: application and biodegradation

T Narancic, F Cerrone, N Beagan, KE O'Connor - Polymers, 2020 - mdpi.com
The success of oil-based plastics and the continued growth of production and utilisation can
be attributed to their cost, durability, strength to weight ratio, and eight contributions to the …

Surface-modified nanocarriers for nose-to-brain delivery: from bioadhesion to targeting

F Sonvico, A Clementino, F Buttini, G Colombo… - Pharmaceutics, 2018 - mdpi.com
In the field of nasal drug delivery, nose-to-brain delivery is among the most fascinating
applications, directly targeting the central nervous system, bypassing the blood brain barrier …

Intranasal delivery of functionalized polymeric nanomaterials to the brain

S Zha, KL Wong, AH All - Advanced Healthcare Materials, 2022 - Wiley Online Library
Intravenous delivery of nanomaterials containing therapeutic agents and various cargos for
treating neurological disorders is often constrained by low delivery efficacy due to difficulties …

Nasal drug delivery of anticancer drugs for the treatment of glioblastoma: preclinical and clinical trials

FA Bruinsmann, G Richter Vaz… - Molecules, 2019 - mdpi.com
Glioblastoma (GBM) is the most lethal form of brain tumor, being characterized by the rapid
growth and invasion of the surrounding tissue. The current standard treatment for …

An update on the role of nanovehicles in nose-to-brain drug delivery

Y Feng, H He, F Li, Y Lu, J Qi, W Wu - Drug discovery today, 2018 - Elsevier
Highlights•NTB drug delivery is emerging as a novel approach for the treatment of CNS
diseases.•DTE and DTP are two main indexes used to evaluate NTB delivery.•A quantitative …

Advances and future perspectives of intranasal drug delivery: A scientometric review

D Xu, XJ Song, X Chen, JW Wang, YL Cui - Journal of Controlled Release, 2024 - Elsevier
Intranasal drug delivery is as a noninvasive and efficient approach extensively utilized for
treating the local, central nervous system, and systemic diseases. Despite numerous …

Management of epileptic disorders using nanotechnology-based strategies for nose-to-brain drug delivery

M Shringarpure, S Gharat, M Momin… - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction Epilepsy, a major neurological disorder affects about 1% of the Indian
population. The discovery of noninvasive strategies for epilepsy presents a challenge for the …

[HTML][HTML] Nucleic acid-based therapy for brain cancer: Challenges and strategies

Z Zhang, J Conniot, J Amorim, Y **, R Prasad… - Journal of Controlled …, 2022 - Elsevier
Nucleic acid-based therapy emerges as a powerful weapon for the treatment of tumors
thanks to its direct, effective, and lasting therapeutic effect. Encouragingly, continuous …

Hyaluronic acid-modified and verteporfin-loaded polylactic acid nanogels promote scarless wound healing by accelerating wound re-epithelialization and controlling …

K Chen, Y Liu, X Liu, Y Guo, J Liu, J Ding… - Journal of …, 2023 - Springer
Wound healing is a common occurrence. However, delayed healing and aberrant scarring
result in pathological wound healing. Accordingly, a scarless wound healing remains a …