The human MHC class I chain-related genes (MICA and MICB) are located within the HLA
class I region of chromosome 6. Their organization, expression and products differ …

The ancient disease of leprosy can cause severe disability and disfigurement and is still a
major health concern in many parts of the world. Only a subset of those individuals exposed …

NK cells are critical components of our immune system functioning, in part, to recognize and
then eradicate virally infected or tumorigenic cells without previous sensitization. One of the …

Following the decision to hold their next full meeting after the 13th International
Histocompatibility Workshop in 2002, the WHO Nomenclature Committee for Factors of the …

Immune effector cells in patients with multiple myeloma (MM) are at the forefront of many
immunotherapy treatments, and several methods have been developed to fully utilise the …

Even when kidney allografts are well matched for human leukocyte antigen (HLA) and anti-
HLA antibodies are not detected, graft rejection can still occur. There is evidence that some …

Since the complete sequencing of a human major histocompatibility complex (MHC)
haplotype, interest in non-human leucocyte antigen (HLA) genes encoded in the MHC has …

In a study of mainly paucibacillary leprosy-affected sib-pair families from South India, in
addition to the expected associations with the HLA-DRB1 locus, we have identified …

Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disorder of unknown
etiology. IPF is likely the result of complex interrelationships between environmental and …

The NKG2D receptor is expressed on the surface of NK, T, and macrophage lineage cells
and plays an important role in antiviral and antitumor immunity. To evade NKG2D …