[HTML][HTML] Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control
P Eisenhut, N Marx, G Borsi, M Papež, C Ruggeri… - New …, 2024 - Elsevier
Mammalian cells have developed dedicated molecular mechanisms to tightly control
expression levels of their genes where the specific transcriptomic signature across all genes …
expression levels of their genes where the specific transcriptomic signature across all genes …
Creative approaches using proximity labeling to gain new biological insights
RR Milione, BB Schell, CJ Douglas… - Trends in Biochemical …, 2024 - cell.com
At its most fundamental level, life is a collection of synchronized cellular processes driven by
interactions among biomolecules. Proximity labeling has emerged as a powerful technique …
interactions among biomolecules. Proximity labeling has emerged as a powerful technique …
Hybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments
K Yap, TH Chung, EV Makeyev - Molecular Cell, 2022 - cell.com
The ability of RNAs to form specific contacts with other macromolecules provides an
important mechanism for subcellular compartmentalization. Here we describe a suite of …
important mechanism for subcellular compartmentalization. Here we describe a suite of …
From genes to traits: Trends in RNA-binding proteins and their role in plant trait development: A review
S Rehman, S Bahadur, W ** in live cells
B Chen, H Shi, J Zhang, C Zhou, M Han… - Biochemical and …, 2021 - Elsevier
RNA-binding proteins (RBPs) are involved in all aspects of RNA metabolism, and RNA-RBP
interactions are important for cell homeostasis and viral replication. The global RNA-binding …
interactions are important for cell homeostasis and viral replication. The global RNA-binding …
Proximity-dependent biotinylation technologies for map** RNA-protein interactions in live cells
R Giambruno, F Nicassio - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Proximity ligation technologies are extremely powerful tools for unveiling RNA-protein
interactions occurring at different stages in living cells. These approaches mainly rely on the …
interactions occurring at different stages in living cells. These approaches mainly rely on the …
Methods to analyze the non-coding RNA interactome—recent advances and challenges
H Cao, P Kapranov - Frontiers in Genetics, 2022 - frontiersin.org
Most of the human genome is transcribed to generate a multitude of non-coding RNAs.
However, while these transcripts have generated an immense amount of scientific interest …
However, while these transcripts have generated an immense amount of scientific interest …
Multiple Oligo assisted RNA Pulldown via Hybridization followed by Mass Spectrometry (MORPH-MS) for exploring the RNA-Protein interactions
Understanding RNA-protein interactions is crucial for deciphering the cellular functions and
molecular mechanisms of regulatory RNAs. Consequently, there is a constant need to …
molecular mechanisms of regulatory RNAs. Consequently, there is a constant need to …
BioID proximity map** reveals novel SAP18 interactions in the prespliceosomal complex
SAP18 protein was originally discovered in association with the SIN3 transcriptional
repressor complex. Subsequent biochemical fractionation studies identified SAP18 as a …
repressor complex. Subsequent biochemical fractionation studies identified SAP18 as a …