[HTML][HTML] Ultrasound neuromodulation: planning and validating treatments

MK Sigona, CF Caskey - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights•Pre-print discusses biophysical safety in transcranial focused
ultrasound.•Identifies thermal and mechanical risks in focused ultrasound.• …

Device for multifocal delivery of ultrasound into deep brain regions in humans

T Riis, D Feldman, A Losser, B Mickey… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Low-intensity focused ultrasound provides the means to noninvasively stimulate or release
drugs in specified deep brain targets. However, successful clinical translations require …

[HTML][HTML] Sustained modulation of primate deep brain circuits with focused ultrasonic waves

TD Webb, MG Wilson, H Odéen, J Kubanek - Brain stimulation, 2023 - Elsevier
Background Transcranial focused ultrasound has the potential to noninvasively modulate
deep brain circuits and impart sustained, neuroplastic effects. Objective Bring the approach …

Controlled noninvasive modulation of deep brain regions in humans

T Riis, D Feldman, B Mickey, J Kubanek - Communications Engineering, 2024 - nature.com
Transcranial focused ultrasound provides noninvasive and reversible approaches for
precise and personalized manipulations of brain circuits, with the potential to transform our …

Noninvasive modulation of essential tremor with focused ultrasonic waves

TS Riis, AJ Losser, P Kassavetis… - Journal of Neural …, 2024 - iopscience.iop.org
Objective: Transcranial focused low-intensity ultrasound has the potential to noninvasively
modulate confined regions deep inside the human brain, which could provide a new tool for …

Controlled ultrasonic interventions through the human skull

MG Wilson, TS Riis, J Kubanek - Frontiers in Human Neuroscience, 2024 - frontiersin.org
Transcranial focused ultrasound enables precise and non-invasive manipulations of deep
brain circuits in humans, promising to provide safe and effective treatments of various …

[HTML][HTML] Remotely controlled drug release in deep brain regions of non-human primates

MG Wilson, TD Webb, H Odéen, J Kubanek - Journal of Controlled Release, 2024 - Elsevier
Many areas of science and medicine would benefit from selective release of drugs in
specific regions. Nanoparticle drug carriers activated by focused ultrasound—remotely …

Remotely induced electrical modulation of deep brain circuits in non-human primates

C Lybbert, T Webb, MG Wilson, K Tsunoda… - Frontiers in Human …, 2024 - frontiersin.org
Introduction The combination of magnetic and focused ultrasonic fields generates focused
electric fields at depth entirely noninvasively. This noninvasive method may find particularly …

Neural correlates of behavioral recovery following ultrasonic thalamic stimulation in chronic disorders of consciousness

JA Cain, NM Spivak, JP Coetzee, JS Crone… - medRxiv, 2023 - medrxiv.org
Background Treatments aimed at hastening recovery from disorders of consciousness
(DOC; eg, coma, the vegetative state) have lagged behind a rapidly advancing science of …

A Physiological Marker for Deep Brain Ultrasonic Neuromodulation

TD Webb, C Lybbert, MG Wilson, H Odéen… - … : Technology at the …, 2025 - Elsevier
Objectives Transcranial ultrasound neuromodulation (TUSN) is a noninvasive and spatially
specific therapy that promises to deliver treatments tailored to the specific needs of …