Physics of brain cancer: Multiscale alterations of glioblastoma cells under extracellular matrix stiffening

M Khoonkari, D Liang, M Kamperman, FAE Kruyt… - Pharmaceutics, 2022 - mdpi.com
The biology and physics underlying glioblastoma is not yet completely understood, resulting
in the limited efficacy of current clinical therapy. Recent studies have indicated the …

Postmortem brain donations vs premortem surgical resections for glioblastoma research: viewing the matter as a whole

CP Griffin, CL Paul, KL Alexander… - Neuro-Oncology …, 2022 - academic.oup.com
There have been limited improvements in diagnosis, treatment, and outcomes of primary
brain cancers, including glioblastoma, over the past 10 years. This is largely attributable to …

Supratentorial masses: anesthetic considerations

JG Gaudet, P Schoettker, NJ Bruder - Cottrell & Patel's Neuroanesthesia, 2025 - Elsevier
The perioperative goals for supratentorial craniotomy are to reduce the risk of secondary
insult to the brain by maintaining intracranial and systemic homeostasis, optimize surgical …

Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibition

IC Sorribes, SK Handelman… - Journal of the Royal …, 2020 - royalsocietypublishing.org
Glioblastomas are among the most lethal cancers, with a 5 year survival rate below 25%.
Temozolomide is typically used in glioblastoma treatment; however, the enzymes …

Mechanical Properties of Glioblastoma: Perspectives for YAP/TAZ Signaling Pathway and Beyond

B Pontes, FA Mendes - Diseases, 2023 - mdpi.com
Glioblastoma is a highly aggressive brain tumor with a poor prognosis. Recent studies have
suggested that mechanobiology, the study of how physical forces influence cellular …

Retrospective longitudinal assessment of optic nerve sheath diameter in patients with malignant glioma

D Feucht, SR Kerscher, C Ruff… - Cancer …, 2023 - Wiley Online Library
Introduction Glioblastoma (GBM) is a tumor with rapid growth and a possible relationship to
elevated intracranial pressure (ICP). High ICP may not always be associated with clinical …

Predicting convection configurations in coupled fluid–porous systems

M McCurdy, NJ Moore, X Wang - Journal of Fluid Mechanics, 2022 - cambridge.org
A ubiquitous arrangement in nature is a free-flowing fluid coupled to a porous medium, for
example a river or lake lying above a porous bed. Depending on the environmental …

Advancements and challenges in brain cancer therapeutics

F Bai, Y Deng, L Li, M Lv, J Razzokov, Q Xu, Z Xu… - …, 2024 - Wiley Online Library
Treating brain tumors requires a nuanced understanding of the brain, a vital and delicate
organ. Location, size, tumor type, and surrounding tissue health are crucial in develo** …

Hemodynamic Imaging in Cerebral Diffuse Glioma—Part A: Concept, Differential Diagnosis and Tumor Grading

L Guida, V Stumpo, J Bellomo, CHB van Niftrik… - Cancers, 2022 - mdpi.com
Simple Summary Diffuse gliomas, and glioblastomas, in particular, represent a diagnostic
and clinical challenge. Standard neuroimaging continues to have many limitations for …

[HTML][HTML] Mendelian randomization combined with multi-omics explores the relationship between heart failure and cancer

T Sun, N Mei, Y Su, S Shan, W Qian, M Li… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Whether there is an association between HF (HF) and cancer has not been
conclusively established, and it is not clear whether patients with cancer can share similar …