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[HTML][HTML] The mammalian circadian system: a hierarchical multi-oscillator structure for generating circadian rhythm
S Honma - The Journal of Physiological Sciences, 2018 - Elsevier
The circadian nature of physiology and behavior is regulated by a circadian clock that
generates intrinsic rhythms with a periodicity of approximately 24 h. The mammalian …
generates intrinsic rhythms with a periodicity of approximately 24 h. The mammalian …
Roles of neuropeptides, VIP and AVP, in the mammalian central circadian clock
D Ono, K Honma, S Honma - Frontiers in neuroscience, 2021 - frontiersin.org
In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of
the hypothalamus. Individual SCN cells exhibit intrinsic oscillations, and their circadian …
the hypothalamus. Individual SCN cells exhibit intrinsic oscillations, and their circadian …
The suprachiasmatic nucleus at 50: looking back, then looking forward
It has been 50 years since the suprachiasmatic nucleus (SCN) was first identified as the
central circadian clock and 25 years since the last overview of developments in the field was …
central circadian clock and 25 years since the last overview of developments in the field was …
Coupled network of the circadian clocks: a driving force of rhythmic physiology
The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …
beings, including humans, to anticipate and adapt to daily changes in their environment. In …
Circadian clocks, cognition, and Alzheimer's disease: synaptic mechanisms, signaling effectors, and chronotherapeutics
KR Hoyt, K Obrietan - Molecular neurodegeneration, 2022 - Springer
Modulation of basic biochemical and physiological processes by the circadian timing system
is now recognized as a fundamental feature of all mammalian organ systems. Within the …
is now recognized as a fundamental feature of all mammalian organ systems. Within the …
Single‐cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin‐driven circadian network
Circadian rhythms in mammals are governed by the hypothalamic suprachiasmatic nucleus
(SCN), in which 20,000 clock cells are connected together into a powerful time‐kee** …
(SCN), in which 20,000 clock cells are connected together into a powerful time‐kee** …
The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus
In mammals, the daily rhythms of physiological functions are timed by the central circadian
clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Although the …
clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Although the …
Dual-color single-cell imaging of the suprachiasmatic nucleus reveals a circadian role in network synchrony
The suprachiasmatic nucleus (SCN) acts as a master pacemaker driving circadian behavior
and physiology. Although the SCN is small, it is composed of many cell types, making it …
and physiology. Although the SCN is small, it is composed of many cell types, making it …
Decoupling PER phosphorylation, stability and rhythmic expression from circadian clock function by abolishing PER-CK1 interaction
Robust rhythms of abundances and phosphorylation profiles of PERIOD proteins were
thought be the master rhythms that drive mammalian circadian clock functions. PER stability …
thought be the master rhythms that drive mammalian circadian clock functions. PER stability …
Network-driven intracellular cAMP coordinates circadian rhythm in the suprachiasmatic nucleus
The mammalian central circadian clock, located in the suprachiasmatic nucleus (SCN),
coordinates the timing of physiology and behavior to local time cues. In the SCN, second …
coordinates the timing of physiology and behavior to local time cues. In the SCN, second …