Nuclear compartments: an incomplete primer to nuclear compartments, bodies, and genome organization relative to nuclear architecture

AS Belmont - Cold Spring Harbor perspectives in biology, 2022 - cshperspectives.cshlp.org
This work reviews nuclear compartments, defined broadly to include distinct nuclear
structures, bodies, and chromosome domains. It first summarizes original cytological …

The nucleolus: structure/function relationship in RNA metabolism

D Hernandez‐Verdun, P Roussel… - Wiley …, 2010 - Wiley Online Library
The nucleolus is the ribosome factory of the cells. This is the nuclear domain where
ribosomal RNAs are synthesized, processed, and assembled with ribosomal proteins. Here …

Genomic repeats categorize genes with distinct functions for orchestrated regulation

JY Lu, W Shao, L Chang, Y Yin, T Li, H Zhang, Y Hong… - Cell reports, 2020 - cell.com
Repetitive elements are abundantly distributed in mammalian genomes. Here, we reveal a
striking association between repeat subtypes and gene function. SINE, L1, and low …

lncRNA maturation to initiate heterochromatin formation in the nucleolus is required for exit from pluripotency in ESCs

N Savić, D Bär, S Leone, SC Frommel, FA Weber… - Cell stem cell, 2014 - cell.com
The open chromatin of embryonic stem cells (ESCs) condenses into repressive
heterochromatin as cells exit the pluripotent state. How the 3D genome organization is …

Serial block face scanning electron microscopy in cell biology: Applications and technology

D Smith, T Starborg - Tissue and Cell, 2019 - Elsevier
Three-dimensional electron microscopy (3DEM) is an imaging field containing several
powerful modalities such as serial section transmission electron microscopy and electron …

Large-scale chromatin organization: the good, the surprising, and the still perplexing

AS Belmont - Current opinion in cell biology, 2014 - Elsevier
Traditionally large-scale chromatin structure has been studied by microscopic approaches,
providing direct spatial information but limited sequence context. In contrast, newer 3C …

Serial block face scanning electron microscopy—the future of cell ultrastructure imaging

L Hughes, C Hawes, S Monteith, S Vaughan - Protoplasma, 2014 - Springer
One of the major drawbacks in transmission electron microscopy has been the production of
three-dimensional views of cells and tissues. Currently, there is no one suitable 3D …

Functional ultrastructure of the plant nucleolus

D Stępiński - Protoplasma, 2014 - Springer
Nucleoli are nuclear domains present in almost all eukaryotic cells. They not only specialize
in the production of ribosomal subunits but also play roles in many fundamental cellular …

Transition metal complexes with the quinolone antibacterial agent pipemidic acid: synthesis, characterization and biological activity

EK Efthimiadou, Y Sanakis, N Katsaros, A Karaliota… - Polyhedron, 2007 - Elsevier
Nine new mononuclear metal complexes of the quinolone antibacterial agent pipemidic acid
(= HPPA) with VO2+, Mn2+, Fe3+, Co2+, Ni2+, Zn2+, MoO22+, Cd2+ and UO22+ have been …

Revealing the high-resolution three-dimensional network of chromatin and interchromatin space: a novel electron-microscopic approach to reconstructing nuclear …

J Rouquette, C Genoud, GH Vazquez-Nin, B Kraus… - Chromosome …, 2009 - Springer
The nuclear architecture is considered an important contributor to genome function.
Although the fine structural features of the cell nucleus have been investigated extensively …